Surface treatment of 45S5 Bioglass using femtosecond laser to achieve superior growth of hydroxyapatite
Surface treatment of 45S5 Bioglass using femtosecond laser to achieve superior growth of hydroxyapatite
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使用飞秒激光对 45S5 生物玻璃进行表面处理，以实现羟基磷灰石的优异生长
DOI：
10.2351/1.4979304
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
S. Sinha
中科院分区：
文献类型：
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作者：
Shazia Shaikh;S. Kedia;Ashutosh Kumar Singh;K. Sharma;S. Sinha
45S5 Hench玻璃（BG）由于其潜在的临床应用而引起了研究兴趣。已经进行了几项体内和体外研究，以提高这种玻璃的生物整合效率。在目前的贡献，亨氏BG的表面改性已经完成采用飞秒（fs）激光束，导致增加的有效表面积的样品。随后将这些表面改性的样品浸入模拟体液中不同的天数，并使用扫描电子显微镜、能量色散X射线分析、X射线衍射和显微拉曼光谱进行表征。体外研究表明，与未处理的样品相比，激光处理的样品上羟基磷灰石（HAP）层的生长上级。强X射线衍射峰的存在证实了HAP在激光处理的样品上的更快生长。拉曼峰，五倍更强和相对更窄，表示激光处理的BG上的羟基磷灰石层的结晶度更高。
45S5 Hench bioglass (BG) has gained interest in research because of its potential clinical applications. Several studies in-vivo and in-vitro have been in progress to improve biointegration efficiency of this glass. In present contribution, surface modification of Hench BG has been done employing a femtosecond (fs) laser beam, resulting in increased effective surface area of the sample. These surface modified samples were subsequently immersed in simulated body fluid for varying number of days and characterized using scanning electron microscope, energy dispersive X-ray analysis, X-ray diffraction, and micro-Raman spectroscopy. In-vitro studies indicated superior growth of hydroxyapatite (HAP) layer on the laser treated samples in comparison to the untreated samples. The presence of strong X-ray diffraction peaks confirmed faster growth of HAP on laser treated samples. Raman peaks, five times more intense and relatively narrower represented higher crystallinity of hydroxyapatite layer on laser treated BG.