Preferential Enrichment of DL-Leucine Using Cocrystal Formation with Oxalic Acid under Nonequilibrium Crystallization Conditions.
Preferential Enrichment of DL-Leucine Using Cocrystal Formation with Oxalic Acid under Nonequilibrium Crystallization Conditions.
复制标题
在非平衡结晶条件下利用草酸共晶形成优先富集 DL-亮氨酸。
作者：
Manoj;K.;Takahashi;H.;Morita;Y.;Gonnade;R. G.;Iwama;S.;Tsue;H.;Tamura;R.
利用优先富集（PE）技术，我们利用DL - Leu和草酸的1:1共晶（DL - 1），提高了DL - Leu （Leu）的对映体分辨率。dl - 1的晶体结构分析表明，发生了一种新型的相变，并随后从所得晶体中优先地将一个对映体再溶解到溶液中。手性27:405-410 2015。©2015 Wiley期刊公司
By utilizing the preferential enrichment (PE) technique, we achieved an improved enantiomeric resolution ofDL‐leucine (Leu) using a 1:1 cocrystal (DL‐1) ofDL‐Leu and oxalic acid. The crystal structure analysis ofDL‐1indicated the occurrence of a novel type of phase transition and subsequent preferential redissolution of one enantiomer from the resulting crystals into solution.Chirality 27:405–410 2015. © 2015 Wiley Periodicals, Inc.