CONSERVATION OF BLADDER FUNCTION IN PATIENTS WITH INVASIVE BLADDER-CANCER TREATED BY DEFINITIVE IRRADIATION AND SELECTIVE CYSTECTOMY
CONSERVATION OF BLADDER FUNCTION IN PATIENTS WITH INVASIVE BLADDER-CANCER TREATED BY DEFINITIVE IRRADIATION AND SELECTIVE CYSTECTOMY
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DOI：
10.1016/0360-3016(81)90367-9
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发表时间：
1981-01-01
影响因子：
7
通讯作者：
BALFOUR, J
中科院分区：
文献类型：
--
作者：
GOODMAN, GB;HISLOP, TG;BALFOUR, J
Patients (470) with invasive bladder cancer treated by definitive irradiation (5000 rad or more) and selective cystectomy were followed to assess their survival status and bladder function status. (A total of 90% were followed for at least 10 yr or to death.) The survival rates for these patients were similar to those obtained in studies of preoperative irradiation with compulsory cystectomy; 5 and 10 yr survival rates were 38 and 22%, respectively. Sixty-five to 70% of these survivors lived with healthy, functioning bladders to at least 10 yr after treatment. Seventy-five patients had a selective cystectomy, usually for recurrent disease, with an operative mortality rate of 11%. Pre-irradiation catheterization, used to control bladder distension and to reduce the possibility of geographic miss in irradiating the tumor, had no effect on the control of local disease or on the long-term survival of patients. Definitive irradiation with selective cystectomy apparently warrants serious consideration in treating patients with invasive bladder cancer, especially considering the quality of life and the high proportion of patients who retain functioning bladders.
