HUMAN-IMMUNODEFICIENCY-VIRUS AND MALARIA IN A REPRESENTATIVE SAMPLE OF CHILDBEARING WOMEN IN KIGALI, RWANDA
HUMAN-IMMUNODEFICIENCY-VIRUS AND MALARIA IN A REPRESENTATIVE SAMPLE OF CHILDBEARING WOMEN IN KIGALI, RWANDA
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DOI：
10.1093/infdis/164.1.67
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发表时间：
1991-07-01
影响因子：
6.4
通讯作者：
HULLEY, S
中科院分区：
文献类型：
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作者：
ALLEN, S;VANDEPERRE, P;HULLEY, S
在1986-1987年的连续样本的3702名妇女提出的产前和儿科诊所在唯一的医院在卢旺达基加利，进行了筛选人类免疫缺陷病毒（HIV）和疟疾感染。 HIV抗体阳性率为29%，疟原虫感染率为9%。 艾滋病毒抗体在城市中心的妇女中比在郊区的妇女中更普遍（31%对20%，P <0.001），疟疾寄生虫显示出相反的流行模式（8%对15%，P <0.001）;在按地点分层后，艾滋病毒与疟疾寄生虫血症的存在或程度之间没有关联。 在1980-1985年期间（在捐献血液筛查开始之前）接受过输血的妇女中，艾滋病毒感染率为45%，在绝大多数（94%）从未接受过输血的妇女中，艾滋病毒感染率为28%。 艾滋病毒感染率在单身母亲中为44%，在同居妇女中为34%，在法律的婚姻中为20%。 基加利一般人口的高感染率突出表明，需要制定有效的方案，防止性传播艾滋病毒的进一步传播。
In 1986-1987 a consecutive sample of 3702 women presenting to prenatal and pediatric clinics at the only hospital in Kigali, Rwanda, was screened for human immunodeficiency virus (HIV) and malaria infection. The prevalence of HIV antibodies was 29%, and that of malaria parasites was 9%. HIV antibodies were more prevalent in women from the urban center than in those from the outskirts (31% vs. 20%, P < .001), and malaria parasites showed the opposite prevalence pattern (8% vs. 15%, P < .001); after stratifying by location, there was no association between HIV and the presence or degree of malaria parasitemia. HIV prevalence was 45% in women who had received a blood transfusion between 1980-1985 (before screening of donated blood began), and 28% among the great majority (94%) who had never been transfused. HIV prevalence was 44% in single mothers, 34% in women in common law unions, and 20% in those in legal marriages. These high rates of infection in the general population of Kigali highlight the need to develop effective programs for preventing further spread of sexually transmitted HIV.