Prevalence, correlates, and course of minor depression and major depression in the national comorbidity survey

Prevalence, correlates, and course of minor depression and major depression in the national comorbidity survey
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DOI:
10.1016/s0165-0327(97)00056-6
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发表时间:
1997-08-01
影响因子:
6.6
通讯作者:
Swartz, M
Swartz, M
中科院分区:
医学2区
文献类型:
--
作者:
Kessler, RC;Zhao, SY;Swartz, M

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来自国家共病调查的数据被用于研究轻度抑郁症(mo)、有5-6种症状的重度抑郁症(MD 5-6)和有7种或7种以上症状的重度抑郁症(MD 7-9)的终生患病率、相关性、病程和损害,以确定mo是否与MD持续存在。以及父母的精神病史从0到5-6再到7-9然而,在大多数情况下,mo和MD 5-6之间的差异并不大于MD 5-6和MD 7-9之间的差异,这表明mo和MD之间存在连续性。再加上早期研究发现亚临床抑郁症是重度抑郁症的重要危险因素,这些结果表明,轻度抑郁症是抑郁症的一种变体,应该被认真考虑作为预防干预和治疗的目标。本文最后提出了对未来纵向研究中mo亚型分析的建议。(C) 1997爱思唯尔科学有限公司
Data from the National Comorbidity Survey are used to study the lifetime prevalences, correlates, course and impairments associated with minor depression (mo), major depression with 5-6 symptoms (:MD 5-6), and major depression with seven or more symptoms (MD 7-9) in an effort to determine whether mo is on a continuum with MD, There is a monotonic increase in average number of episodes, average length of longest episode, impairment, comorbidity, and parental history of psychiatric disorders as we go from mo to MD 5-6 to MD 7-9. In most of these cases, though, the differences between mo and MD 5-6 are no larger than the differences between MD 5-6 and MD 7-9,arguing for continuity between mo and MD. Coupled with the finding from earlier studies that subclinical depression is a significant risk factor for major depression, these results argue that minor depression is a variant of depressive disorder that should be considered seriously both as a target for preventive intervention and for treatment. The paper closes with suggestions regarding the analysis of mo subtypes in future longitudinal studies. (C) 1997 Elsevier Science B.V.