A Test and Review of the Role of Effective Population Size on Experimental Sexual Selection Patterns
A Test and Review of the Role of Effective Population Size on Experimental Sexual Selection Patterns
复制标题
有效种群规模对实验性选择模式作用的检验和回顾
DOI：
10.1111/j.1558-5646.2009.00682.x
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发表时间：
2009
期刊：
影响因子：
8.8
通讯作者：
J. Slate
中科院分区：
文献类型：
--
作者：
R. Snook;Lena Brüstle;J. Slate
实验进化，特别是通过改变交配系统来操纵性选择强度的实验性别选择，是检验进化理论的一种日益流行的方法。不同试验处理间的遗传多样性差异引起了人们的关注：育种者数量和性别比例的差异(有效种群数量；Ne)以及基因搭便车的可能性，这两者都可能导致不同处理之间的遗传差异水平。这种差异可能会影响选择反应和对结果的混乱解释。在这里，我们使用基于普查的估计者和基于分子标记的估计值来经验地测试拟黑果蝇性别选择的实验进化如何影响Ne和常染色体遗传多样性。我们还考虑了治疗对X连锁NE的影响，这一点以前被忽视了。基于分子常染色体标记的估计值表明，在经历不同性别选择强度的处理之间，Ne和遗传多样性都没有不同；因此，观察到的进化反应反映了选择，而不是实验设计的任何混淆效果。鉴于关于实验性性别选择的研究越来越多，我们还回顾了其他实验系统的普查NE，计算X连锁NE，并比较不同研究如何处理近亲繁殖、遗传漂移和遗传搭便车问题，以帮助为未来的设计提供信息。
Experimental evolution, particularly experimental sexual selection in which sexual selection strength is manipulated by altering the mating system, is an increasingly popular method for testing evolutionary theory. Concerns have arisen regarding genetic diversity variation across experimental treatments: differences in the number and sex ratio of breeders (effective population size; Ne) and the potential for genetic hitchhiking, both of which may cause different levels of genetic variation between treatments. Such differences may affect the selection response and confound interpretation of results. Here we use both census-based estimators and molecular marker-based estimates to empirically test how experimental evolution of sexual selection in Drosophila pseudoobscura impacts Ne and autosomal genetic diversity. We also consider effects of treatment on X-linked Nes, which have previously been ignored. Molecular autosomal marker-based estimators indicate that neither Ne nor genetic diversity differs between treatments experiencing different sexual selection intensities; thus observed evolutionary responses reflect selection rather than any confounding effects of experimental design. Given the increasing number of studies on experimental sexual selection, we also review the census Nes of other experimental systems, calculate X-linked Ne, and compare how different studies have dealt with the issues of inbreeding, genetic drift, and genetic hitchhiking to help inform future designs.