Japanese population norms for preference-based measures: EQ-5D-3L, EQ-5D-5L, and SF-6D.
Japanese population norms for preference-based measures: EQ-5D-3L, EQ-5D-5L, and SF-6D.
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DOI：
10.1007/s11136-015-1108-2
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发表时间：
2016-03
期刊：
影响因子：
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通讯作者：
Shimozuma K
中科院分区：
文献类型：
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作者：
Shiroiwa T;Fukuda T;Ikeda S;Igarashi A;Noto S;Saito S;Shimozuma K
本研究的目的是测量日本版基于偏好的测量（EQ-5D-3L、EQ-5D-5L和SF-6D）的人群标准。我们还考虑了一般人群的生活质量评分与社会人口学因素之间的关系。 使用基本居民登记册的数据，从日本各地随机抽取了1143名成年受访者（年龄≥ 20岁）。使用EQ-5D-3L、EQ-5D-5L和SF-6D测量每位受访者的健康状况，并获得关于社会人口学数据以及主观疾病和症状的回答。使用日本值集将回答转换为QOL评分。 具有完整健康评分的受访者百分比分别为68%（EQ-5D-3L）、55%（EQ-5D-5L）和4%（SF-6D）。使用SF-6D测量的QOL评分显著低于使用EQ-5D评分测量的QOL评分。60岁以上、收入较低和受教育时间较短的受访者的生活质量得分明显较低。组内相关系数显示EQ-5D和SF-6D评分之间的一致性较差。对于EQ-5D-3L、EQ-5D-5L和SF-6D，有和无任何疾病的受访者之间的QOL评分差异分别为0.064、0.061和0.073;这些差异被视为一般人群中的组间最小重要差异。 首次对三种基于偏好的生活质量指标的日本人群标准进行了研究。这些信息对于经济评估和研究QOL评分是有用的。
The purpose of this study was to measure the population norms for the Japanese versions of preference-based measures (EQ-5D-3L, EQ-5D-5L, and SF-6D). We also considered the relations between QOL score in the general population and socio-demographic factors. A total of 1143 adult respondents (aged ≥ 20 years) were randomly sampled from across Japan using data from the Basic Resident Register. The health status of each respondent was measured using the EQ-5D-3L, EQ-5D-5L, and SF-6D, and responses regarding socio-demographic data as well as subjective diseases and symptoms were obtained. The responses were converted to a QOL score using Japanese value sets. The percentages of respondents with full health scores were 68 % (EQ-5D-3L), 55 % (EQ-5D-5L), and 4 % (SF-6D). The QOL score measured using the SF-6D was significantly lower than those measured using either EQ-5D score. The QOL score was significantly lower among respondents over the age of 60 years, those who had a lower income, and those who had a shorter period of education. Intraclass correlation coefficient showed a poor agreement between the EQ-5D and SF-6D scores. The differences in QOL scores between respondents with and those without any disease were 0.064 for the EQ-5D-3L, 0.061 for the EQ-5D-5L, and 0.073 for the SF-6D; these differences are regarded as between-group minimal important differences in the general population. The Japanese population norms of three preference-based QOL measures were examined for the first time. Such information is useful for economic evaluations and research examining QOL score.