Association between Ideal Cardiovascular Health Metrics and Depression in Chinese Population: A Cross-sectional Study.
Association between Ideal Cardiovascular Health Metrics and Depression in Chinese Population: A Cross-sectional Study.
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DOI：
10.1038/srep11564
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发表时间：
2015-07-15
影响因子：
4.6
通讯作者：
Wang X
中科院分区：
文献类型：
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作者：
Li Z;Yang X;Wang A;Qiu J;Wang W;Song Q;Wang X
该研究旨在研究理想心血管健康（CVH）指标与抑郁症之间的关系。我们对居住在中国唐山市的6，851名年龄在20岁或以上的参与者（3，525名男性和3，326名女性）进行了一项基于人群的横断面研究。通过问卷调查、体格检查和实验室检查收集7项CVH指标（包括吸烟、体重指数、饮食摄入、体力活动、血压、总胆固醇和空腹血糖）的信息。使用流行病学研究抑郁量表（CES-D）评估抑郁状态，评分为16分或以上被视为抑郁。采用Logistic回归分析CVH指标与抑郁的关系。在6，851名参与者中，525人（7.7%）处于抑郁状态。在调整潜在混杂因素后，理想CVH指标汇总评分最高四分位数的男性与最低四分位数的男性相比，患抑郁症的可能性降低（调整后比值比（AOR）：0.46，95%置信区间（CI）：0.28-0.75，p = 0.002）。在女性中也发现了类似的趋势，尽管这种关联并不显著（AOR = 0.74，95%CI：0.46-1.18，p = 0.211）。本研究表明，更好的CVH状态与抑郁症的风险较低，特别是在中国男性和年轻人群。
The study aimed to examine the association between ideal cardiovascular health (CVH) metrics and depression. We conducted a population-based, cross-sectional study of 6,851 participants aged 20 years or older (3,525 men and 3,326 women) living in Tangshan City, China. Information on the seven CVH metrics (including smoking, body mass index, dietary intake, physical activity, blood pressure, total cholesterol and fasting blood glucose) was collected via questionnaires, physical examination and laboratory test. Depression status was assessed using the Epidemiologic Studies Depression Scale (CES-D) and a score of 16 or above was considered depression. The relationship between CVH metrics and depression was analyzed using logistic regression. Of the 6,851 participants, 525 (7.7%) were in depression status. After adjustment for potential confounders, men in the highest quartile of ideal CVH metric summary score had a reduced likelihood of having depression compared to those in the lowest quartile (adjusted odds ratio (AOR): 0.46, 95% confidence interval (CI): 0.28–0.75, p = 0.002). A similar trend was found among women, even though the association was not significant (AOR = 0.74, 95%CI: 0.46–1.18, p = 0.211). This study suggested that better CVH status is associated with a lower risk of depression especially in Chinese male and young population.