Research diagnostic criteria subtypes of depression. Their role as predictors of differential response to psychotherapy and drug treatment.
Research diagnostic criteria subtypes of depression. Their role as predictors of differential response to psychotherapy and drug treatment.
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研究抑郁症亚型的诊断标准。
DOI：
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发表时间：
1980
影响因子：
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通讯作者：
B. Rounsaville
中科院分区：
文献类型：
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作者：
B. Prusoff;M. Weissman;G. Klerman;B. Rounsaville
我们研究了有用的研究诊断标准亚型的预测阿米替林和短期人际心理治疗（IPT）在16周，对照，随机临床试验81例门诊抑郁症患者的反应。情境性抑郁症患者和内源性抑郁症患者对联合治疗均有反应;内源性抑郁症患者对单独IPT无反应，而情境性抑郁症患者对单独IPT或三环类药物有反应。这可能是没有必要提供两种治疗的情况下抑郁症患者。然而，情境性和内源性并不是相互排斥的诊断，并且获得更长的具有这两种诊断的患者组用于进一步研究将是临床感兴趣的。
We studied the usefulness of the research diagnostic criteria subtypes in the prediction of response to amitriptyline and short-term interpersonal psychotherapy (IPT) in a 16-week, controlled, randomized clinical trial with 81 ambulatory depressed patients. Both patients with a situational depression and patients with an endogenous depression responded to combined treatment; those with an endogenous depression did not respond to IPT alone, whereas those with a situational depression responded to IPT or tricyclic medication alone. It may not be necessary to offer both treatments to the situationally depressed patients. However, situational and endogenous are not mutally exclusive diagnoses, and it would be of clinical interest to obtain a longer group of patients with both diagnoses for further study.