Substance of abuse and movement disorders: complex interactions and comorbidities.
Substance of abuse and movement disorders: complex interactions and comorbidities.
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DOI：
10.2174/1874473711205030243
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发表时间：
2012-09
期刊：
影响因子：
--
通讯作者：
Luciano MS
中科院分区：
文献类型：
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作者：
Deik A;Saunders-Pullman R;Luciano MS
我们之前审查的运动障碍和药物滥用之间的关系已更新。我们双向研究这些关系，重点关注导致运动障碍的滥用药物，以及与使用和滥用酒精和多巴胺能药物相关的原发性运动障碍。首先，我们回顾一下因频繁使用或戒断频繁滥用药物（包括酒精、可卡因、海洛因、安非他明和甲卡西酮）可能引起的运动障碍。然后我们评论酒精中毒和酒精反应性运动障碍（例如特发性震颤和肌阵挛肌张力障碍）之间的相互作用。最后，我们讨论了帕金森病 (PD) 患者滥用抗帕金森多巴胺能药物的可能性。
The relationship between movement disorders and substance abuse which we previously reviewed are updated. We examine these relationships bidirectionally with focus on drugs of abuse which cause movement disorders, as well as primary movement disorders that are associated with use and abuse of alcohol and dopaminergic medications. First, we review the movement disorders that may develop from the acute use or withdrawal of frequent drugs of abuse, including alcohol, cocaine, heroin, amphetamine and methcathinone. We then comment on the interaction between alcoholism and alcohol-responsive movement disorders, such as essential tremor and myoclonus-dystonia. Lastly, we discuss the potential for abuse of antiparkinsonian dopaminergic agents in patients with Parkinson’s disease (PD).