Acute renal failure occurring during intravenous desferrioxamine therapy: recovery after haemodialysis.
Acute renal failure occurring during intravenous desferrioxamine therapy: recovery after haemodialysis.
复制标题
静脉去铁胺治疗期间发生的急性肾功能衰竭：血液透析后恢复。
作者：
P. Cianciulli;F. Sorrentino;L. Forte;M. Palombi;G. Papa;C. Meloni;M. Taccone Gallucci;C. Casciani
A patient with transfusion-dependent thalassemia was undergoing home intravenous desferrioxamine (DFX) treatment by means of a totally implanted system because of his poor compliance with the nightly subcutaneous therapy. Due to an accidental malfunctioning of the infusion pump, the patient was inadvertently administered a toxic dosage of the drug which caused renal insufficiency. Given the progressive deterioration of the symptoms and of the laboratory values, despite adequate medical treatment, a decision was made to introduce haemodialytical therapy in order to remove the drug and therapy reduce the nephrotoxicity. From the results obtained, haemodialysis can therefore be suggested as a useful therapy in rare cases of progressive acute renal failure caused by desferrioxamine.
