Associated factors for falls and fear of falling in Japanese patients with rheumatoid arthritis
Associated factors for falls and fear of falling in Japanese patients with rheumatoid arthritis
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DOI：
10.1007/s10067-009-1229-5
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发表时间：
2009-11-01
影响因子：
3.4
通讯作者：
Yamanaka, Hisashi
中科院分区：
文献类型：
--
作者：
Furuya, Takefumi;Yamagiwa, Kiyotaka;Yamanaka, Hisashi
其目的是确定与日本类风湿性关节炎(RA)患者跌倒相关的因素。在参与一项以单一机构为基础的类风湿性关节炎患者前瞻性观察队列研究的患者中，4996人(男性765人，女性4231人，年龄中位数60岁)回答了在2008年4月或5月之前6个月内与跌倒有关的问题。Logistic回归用于确定变量和跌倒之间的关联。505例(10.1%)、110例(2.2%)和958例(19.2%)分别报告至少一次跌倒、多次跌倒和害怕跌倒。与没有跌倒的人相比，跌倒的人在相同的6个月内倾向于报告骨折事件(14.7%对1.1%，P<；0.001)。在多变量模型中，日本健康评估问卷(HAQ)得分(优势比(OR)1.52、2.49和3.88)、压痛关节计数(OR 1.39、1.72和1.36)、患者报告的一般健康视觉模拟评分(OR 1.08、1.16和1.20)以及体重指数(OR 1.05、1.08和1.04)分别与至少一次摔倒、多次摔倒和害怕摔倒相关(P<；0.05)。其他临床变量和药物也与跌倒和跌倒恐惧有关。HAQ残疾评分、关节压痛计数和一般健康受损似乎与日本RA患者跌倒有关，就像之前报道的其他种族患者的跌倒一样。
The objective of this is to determine factors associated with falls in Japanese patients with rheumatoid arthritis (RA). Among the patients who participated in a single-institute-based prospective observational cohort study of patients with RA, namely, Institute of Rheumatology Rheumatoid Arthritis, 4,996 (male 765, female 4231, median age 60 years) responded to questions related to falls during the previous 6 months in April or May 2008. Logistic regression was used to determine the association between variables and falls. Five hundred and five (10.1%), 110 (2.2%), and 958 patients (19.2%) reported at least one fall, multiple falls, and fear of falling, respectively. Those who fell tended to report incident fractures during the same 6 months compared to those who did not (14.7% versus 1.1%, P < 0.001). In multivariate models, Japanese health assessment questionnaire (HAQ) scores (odds ratios (OR) 1.52, 2.49, and 3.88), tender joint counts (OR 1.39, 1.72, and 1.36), patient-reported visual analog scale for general health (OR 1.08, 1.16, and 1.20), and body mass index (OR 1.05, 1.08, and 1.04) were associated (P < 0.05) with at least one fall, multiple falls, and fear of falling, respectively. Other clinical variables and medications were also associated with falls and fear of falling. HAQ disability score, tender joint counts, and impaired general health appear to be associated with falls in Japanese patients with RA, as previously reported for patients of other ethnicities.