Mortality Rates by Age Group and Intubation Status in Hospitalized Adult Patients From 21 United States Hospital Systems During Three Surges of the COVID-19 Pandemic.

Mortality Rates by Age Group and Intubation Status in Hospitalized Adult Patients From 21 United States Hospital Systems During Three Surges of the COVID-19 Pandemic.
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DOI:
10.1016/j.chest.2023.01.029
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发表时间:
2023-06
期刊:
影响因子:
9.6
通讯作者:
Fiore, Michael C.
Fiore, Michael C.
中科院分区:
医学1区
文献类型:
--
作者:
Nolan, Margaret B.;Nolan, Matthew E.;Piasecki, Thomas M.;Fiore, Michael C.

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方法数据来自威斯康星州大学COVID电子健康记录队列研究的住院样本,这是一项由美国国家癌症研究所支持的回顾性队列研究,其中包括2020年2月1日至2022年1月31日期间在21个卫生系统之一住院的149,989名COVID-19患者的电子健康记录。入选标准为:(1)住院≥ 24小时(如果住院期间< 24小时死亡或入住ICU);(2)国际疾病分类-10诊断为COVID-19或COVID-19聚合酶链反应检测结果阳性,入院后±7天;(3)至少有一次与卫生系统的既往联系(为了人口统计学和合并症信息的准确性)。目前的分析仅限于一个子样本(N= 62,848),这些子样本(1)年龄≥ 20岁;(2)国际疾病分类-10诊断为U 07。1(冠状病毒-19/COVID-19),J12. 82(COVID-19引起的肺炎),或U 09。9例(COVID-19后状况,未指明)在入院、出院或就诊期间;(3例)在三个高容量窗口(即“激增”)之一期间入院,大致对应于疾病控制和预防中心定义的SARS-CoV-2的α、δ和omicron显性菌株。3
MethodsData were drawn from the hospitalized sample of the COVID Electronic Health Records Cohort at the University of Wisconsin Study, a retrospective cohort study supported by the National Cancer Institute with electronic health records on 149,989 patients with COVID-19 who were admitted to one of 21 health systems between February 1, 2020, and January 31, 2022. Inclusion criteria were (1) inpatient admission≥ 24 hours (if< 24 h death or ICU admission during hospitalization;(2) International Classification of Diseases-10 diagnosis of COVID-19 or positive COVID-19 polymerase chain reaction test result±7 days from admission; and (3) at least one prior contact with the health system (for accuracy of demographic and comorbidity information). The current analyses were limited to a subsample (N= 62,848) who (1) were≥ 20 years old;(2) had an International Classification of Diseases-10 diagnosis of U07. 1 (Coronavirus-19/COVID-19), J12. 82 (pneumonia caused by COVID-19), or U09. 9 (post COVID-19 condition, unspecified) during admission, discharge, or encounter; and (3) were admitted during one of three high volume windows (ie,“surges”) that roughly corresponded to alpha, delta and omicron-dominant strains of SARS-CoV-2, as defined by the Centers for Disease Control and Prevention. 3
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发表时间: 2022-01-07
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影响因子: --
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