Frequency offset corrected inversion (FOCI) pulses for use in localized spectroscopy

Frequency offset corrected inversion (FOCI) pulses for use in localized spectroscopy
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DOI:
10.1002/mrm.1910360410
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发表时间:
1996-10-01
影响因子:
3.3
通讯作者:
Franconi, F
Franconi, F
中科院分区:
医学3区
文献类型:
--
作者:
Ordidge, RJ;Wylezinska, M;Franconi, F

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梯度局部化光谱技术遭受由共振之间的化学位移的差异引起的有据可查的空间局部化误差。这导致从样品的部分重叠的空间区域获取光谱,其中每个共振表示不同的区域。图像选择的体内光谱技术使用双曲正割反转脉冲,其中减少该误差的主要限制在于可用于施加选择性RF脉冲的RF功率。这种空间定位误差可以通过在切片选择性自旋反转期间增加和时间整形梯度脉冲来显著减小。这些RF脉冲的性能已被实验验证。
Gradient localized spectroscopy techniques suffer from a well documented spatial localization error caused by the difference in chemical shifts between resonances, This results in the acquisition of spectra from partially overlapping spatial regions of the sample, with each resonance representing a different region. The image-selected in vivo spectroscopy technique uses hyperbolic secant inversion pulses, where the main limitation in reducing this error is in the RF power available for application of the selective RF pulse. This spatial localization error may be dramatically reduced by increasing, and temporally shaping, the gradient pulse during slice-selective spin inversion. The performance of these RF pulses have been experimentally verified.