Sequence selective dual-emission detection of (i, i+1) bis-phosphorylated peptide using diazastilbene-type Zn(II)-Dpa chemosensor

Sequence selective dual-emission detection of (i, i+1) bis-phosphorylated peptide using diazastilbene-type Zn(II)-Dpa chemosensor
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DOI:
10.1039/b905814a
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发表时间:
2009-01-01
影响因子:
4.9
通讯作者:
Hamachi, Itaru
Hamachi, Itaru
中科院分区:
化学2区
文献类型:
--
作者:
Ishida, Yoshiyuki;Inoue, Masa-aki;Hamachi, Itaru

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本文描述了一种用于磷酸化肽的新型荧光化学传感器,其包含刚性反式4,4'-二氮杂芪和两个Zn(II)-Dpa(2,2'-二吡啶胺)单元;该化学传感器序列选择性地结合 (i, i + 1) 双磷酸化肽并显示双发射荧光变化。
This paper describes a new fluorescent chemosensor for phosphorylated peptide, which comprises a rigid trans-4,4'-diazastilbene and two Zn(II)-Dpa (2,2'-dipicolylamine) units; this chemosensor sequence-selectively binds to a (i, i + 1) bis-phosphorylated peptide and displays a dual-emission fluorescence change.