Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section.
Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section.
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非创伤性剖宫产后 X 因子缺乏的新生儿出现帽状腱膜下出血。
DOI：
10.1038/jp.2011.122
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Kingma,PS
中科院分区：
文献类型：
--
作者：
Wetzel,EA;Kingma,PS
本病例报告描述了一个足月婴儿出生的非创伤性，非器械剖宫产，表现为呼吸衰竭和严重代谢性酸中毒继发于galeal下出血（SGH）。进一步的评估显示功能因子X缺乏，最初用新鲜冷冻血浆输注治疗。该报告对非创伤性分娩中SGH的发生具有重要意义，并强调了对具有类似表现的患者进行凝血功能评估的重要性。此外，该病例表明，导致SGH的损伤机制可能比以前认为的更频繁发生，但在没有潜在凝血病的患者中并不具有临床意义。
This case report describes a term infant born by a non-traumatic, non-instrumented cesarean section that presented with respiratory failure and severe metabolic acidosis secondary to subgaleal hemorrhage (SGH). Further evaluation revealed a functional factor X deficiency that was initially treated with fresh frozen plasma infusions. This report is significant for the occurrence of a SGH in a non-traumatic delivery and emphasizes the importance of obtaining a coagulopathy evaluation in patients with similar presentations. In addition, this case suggests that the mechanism of injury that causes SGH may occur more frequently than previously thought, but does not become clinically significant in patients without an underlying coagulopathy.