BACT/ALERT - AN AUTOMATED COLORIMETRIC MICROBIAL DETECTION SYSTEM
BACT/ALERT - AN AUTOMATED COLORIMETRIC MICROBIAL DETECTION SYSTEM
复制标题
DOI：
10.1128/jcm.28.7.1608-1612.1990
复制
发表时间：
1990-07-01
影响因子：
9.4
通讯作者：
RELLER, LB
中科院分区：
文献类型：
--
作者：
THORPE, TC;WILSON, ML;RELLER, LB
BacT/Alert（Organon Teknika Corp.，北卡罗来纳州达勒姆）是一种自动微生物检测系统，基于对生长微生物产生的CO2进行比色检测。对培养基、传感器、检测系统和检测算法的评估结果表明，该系统能够可靠地生长并检测各种细菌和真菌。使用原型研究仪器进行的有限试点临床试验的结果表明，该系统在培养和检测血液中微生物的能力方面与辐射BACTEC 460系统相当。在这些初步发现的基础上，将BacT/Alert与其他商业微生物检测系统进行比较的大规模临床试验似乎是必要的。
BacT/Alert (Organon Teknika Corp., Durham, N.C.) is an automated microbial detection system based on the colorimetric detection of CO2 produced by growing microorganisms. Results of an evaluation of the media, sensor, detection system, and detection algorithm indicate that the system reliably grows and detects a wide variety of bacteria and fungi. Results of a limited pilot clinical trial with a prototype research instrument indicate that the system is comparable to the radiometric BACTEC 460 system in its ability to grow and detect microorganisms in blood. On the basis of these initial findings, large-scale clinical trials comparing BacT/Alert with other commercial microbial detection systems appear warranted.