Potential roles of bone marrow stem cells in stroke therapy.

Potential roles of bone marrow stem cells in stroke therapy.
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骨髓干细胞在中风治疗中的潜在作用。

DOI:
10.2217/17460751.2.4.417
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发表时间:
2007
影响因子:
2.7
通讯作者:
J. Oliveira
J. Oliveira
中科院分区:
工程技术4区
文献类型:
--
作者:
R. Mendez;G. D. de Freitas;C. André;M. L. D. de Mendonça;M. Friedrich;J. Oliveira

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在实用性和有效性方面,需要改进中风患者的治疗方法;然而,多年来,许多潜在药物的临床试验未能证明积极的结果。新兴的干细胞研究领域为包括中风在内的神经系统疾病的治疗带来了希望。这篇综述讨论了最近的临床试验和试点研究使用干细胞在中风患者和突出的关键问题,必须解决,以提高成功地开发一个新的战略中风患者使用成人干细胞的机会。
There is a need for improved therapies, in terms of utility and effectiveness, for stroke patients; however, over the years, numerous clinical trials of potential drugs have failed to demonstrate positive results. The emerging field of stem cell research has raised several hopes of a therapy for neurological diseases, including stroke. This review discusses the recent clinical trials and pilot studies using stem cells in stroke patients and highlights key issues that must be addressed to improve the chances of successfully developing a new strategy for stroke patients using adult stem cells.
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发表时间: 2006
影响因子: 2.7
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