Changes in depressive symptoms and cognitive impairment in older long-stay nursing home residents in the USA: a latent transition analysis.

Changes in depressive symptoms and cognitive impairment in older long-stay nursing home residents in the USA: a latent transition analysis.
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DOI:
10.1080/13607863.2020.1849021
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发表时间:
2021-10
影响因子:
3.4
通讯作者:
Ulbricht CM
Ulbricht CM
中科院分区:
医学2区
文献类型:
--
作者:
Yuan Y;Lapane KL;Rothschild AJ;Ulbricht CM

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纵向研究美国老年疗养院(NH)居民抑郁症状的潜伏状态及其与认知障碍的关系。使用最小数据集3.0,确定了2014年新入院的长期住院的老年NH抑郁症患者(n = 88,532)。在入院时和90天时测量抑郁症状(患者健康问卷-9)和认知功能障碍(精神状态简短访谈)。采用潜伏转换分析,以检查的患病率和抑郁症状的潜伏状态之间的过渡,从入院到90天,和认知功能障碍与入院时的状态。确定了抑郁症状的四种潜在状态:“多种症状”(入院时患病率:17.3%; 90天:13.6%)、“抑郁情绪”(20.0%; 19.5%)、“疲劳”(27.4%; 25.7%)和“轻微症状”(35.3%; 41.2%)。大多数居民从入院到90天都保持相同的状态。与认知完整的居民相比,中度损伤的居民更有可能处于“多种症状”和“疲劳”状态;重度损伤的居民属于“多种症状”,“抑郁情绪”和“疲劳”状态的几率较低。通过解决异质性抑郁症状的纵向变化和认知障碍的作用,研究结果对老年NH居民的抑郁症管理有影响。
To longitudinally examine the latent statuses of depressive symptoms and their association with cognitive impairment in older U.S. nursing home (NH) residents. Using Minimum Data Set 3.0, newly-admitted, long-stay, older NH residents with depression in 2014 were identified (n = 88,532). Depressive symptoms (Patient Health Questionnaire-9) and cognitive impairment (Brief Interview of Mental Status) were measured at admission and 90 days. Latent transition analysis was used to examine the prevalence of and the transition between latent statuses of depressive symptoms from admission to 90 days, and the association of cognitive impairment with the statuses at admission. Four latent statuses of depressive symptoms were identified: ‘Multiple Symptoms’ (prevalence at admission: 17.3%; 90 days: 13.6%), ‘Depressed mood’ (20.0%; 19.5%), ‘Fatigue’ (27.4%; 25.7%), and ‘Minimal Symptoms’ (35.3%; 41.2%). Most residents remained in the same status from admission to 90 days. Compared to residents who were cognitively intact, those with moderate impairment were more likely to be in ‘Multiple Symptoms’ and ‘Fatigue’ statuses; those with severe impairment had lower odds of belonging to ‘Multiple Symptoms’, ‘Depressed Mood’, and ‘Fatigue’ statuses. By addressing the longitudinal changes in the heterogeneous depressive symptoms and the role of cognitive impairment, findings have implications for depression management in older NH residents.
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