STANDARDIZATION OF M-MODE ECHOCARDIOGRAPHIC LEFT-VENTRICULAR ANATOMIC MEASUREMENTS
STANDARDIZATION OF M-MODE ECHOCARDIOGRAPHIC LEFT-VENTRICULAR ANATOMIC MEASUREMENTS
复制标题
DOI：
10.1016/s0735-1097(84)80141-2
复制
发表时间：
1984-01-01
影响因子：
24
通讯作者：
LARAGH, JH
中科院分区：
文献类型：
--
作者：
DEVEREUX, RB;LUTAS, EM;LARAGH, JH
为了提高超声心动图左室解剖测量的标准化，超声心动图左室尺寸和质量与体型指标、性别、年龄和血压相关。独立的正常人群包括92名基于医院的受试者（64名女性，28名男性）和133名来自人口样本的受试者（55名女性，78名男性）。在两个系列中，男性和女性的腔室大小、壁厚和质量的所有测量值都不同（P < 0.01至P < 0.001）。在所有4组中，左心室质量与体表面积的关系最为密切（r = 0.37, P < 0.01至r = 0.57, P < 0.001）。体表面积指数消除了壁厚和内部尺寸的性别差异，但左心室质量指数的显著性别差异仍然存在（89 .+-）。男性为21 g/m2，女性为69 + 19 g/m2， P < 0.0001)。两组男性（136和132 g/m2）和女性（112和109 g/m2）的左心室质量指数的第97百分位相同。根据24小时尿肌酸排泄量估算，男性和女性在瘦体重方面存在显著差异（58 .+-）。15 vs. 40。13 kg, P < 0.001)，以瘦体重为指标的左室质量无性别差异(3.4 .+-。1.3 vs. 3.5 .+-1.5克/公斤)。左心室质量/瘦体重与收缩压或舒张压之间存在弱相关性（r = 0.25, P < 0.05和r = 0.28, P < 0.01），但与年龄（18-27岁）无关。左心室尺寸与体表面积显著相关。女性的左心室质量指数比男性低20%，但通过估计的瘦体重指数消除了这种差异。正常范围内的血压变化对左心室质量的影响较小，而年龄对左心室质量没有影响。因此，性别和体表面积应用于确定解剖左心室测量的临床正常范围；通过使用瘦体重测量，可以进一步完善标准。
To improve standardization of echocardiographic left ventricular anatomic measurements, echographic left ventricular dimensions and mass were related to body size indexes, sex, age and blood pressure. Independent normal populations comprised 92 hospital-based subjects (64 women, 28 men) and 133 subjects from a population sample (55 women, 78 men). All measurements of chamber size, wall thickness and mass differd between men and women in both series (P < 0.01 to P < 0.001). Left ventricular mass was related most closely to body surface area among measurements of body size (r = 0.37, P < 0.01 to r = 0.57, P < 0.001) in all 4 groups. Indexation of body surface area eliminated sex differences in wall thicknesses and internal dimension, but a significant sex difference in left ventricular mass index persisted (89 .+-. 21 g/m2 in men vs. 69 + 19 g/m2 in women in the entire series, P < 0.0001). The 97th percentile of left ventricular mass index was identical in both groups of men (136 and 132 g/m2) and women (112 and 109 g/m2). A highly significant difference in lean body mass, estimated from 24 h urine creatine excretion, was observed between men and women (58 .+-. 15 vs. 40 .+-. 13 kg, P < 0.001) and no sex difference existed in left ventricular mass indexed by lean body mass (3.4 .+-. 1.3 vs. 3.5 .+-. 1.5 g/kg). Weak correlations were observed between left ventricular mass/lean body mass and systolic or diastolic blood pressure (r = 0.25, P < 0.05 and r = 0.28, P < 0.01, respectively) but not age (18-27 yr). Left ventricular dimensions are significantly related to body surface area. Left ventricular mass index is 20% less in women than men but indexation by estimated lean body mass eliminates this difference. Blood pressure variation in the normal range affects left ventricular mass weakly whereas age has no effect. Therefore, sex and body surface area should be used to determine clinical normal limits of anatomic left ventricular measurements; further refinement of criteria may be achieved by use of lean body mass measurements.