Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.
Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.
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DOI：
10.1016/s0076-6879(09)04617-5
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发表时间：
2009
影响因子：
--
通讯作者：
Thomas, Jacob
中科院分区：
文献类型：
--
作者：
Cronan, John E.;Thomas, Jacob
本文介绍了目前研究最透彻的细菌脂肪酸合成途径，大肠杆菌，然后讨论了例外的E。大肠杆菌途径存在于其他细菌中。已知的脂肪酸和聚酮合成途径之间的相互关系也进行了评估，主要是在链霉菌群的细菌。最后，我们提出了细菌脂肪酸合成途径的分析方法纲要。
This review presents the most thoroughly studied bacterial fatty acid synthetic pathway, that of Escherichia coli and then discusses the exceptions to the E. coli pathway present in other bacteria. The known interrelationships between the fatty acid and polyketide synthetic pathways are also assessed, mainly in the Streptomyces group of bacteria. Finally, we present a compendium of methods for analysis of bacterial fatty acid synthetic pathways.