HISTOPATHOLOGY OF THE SOFT PARTS IN 50 PATIENTS WITH MALIGNANT EXTERNAL OTITIS
HISTOPATHOLOGY OF THE SOFT PARTS IN 50 PATIENTS WITH MALIGNANT EXTERNAL OTITIS
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DOI：
10.1017/s0022215100108977
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发表时间：
1989-04-01
影响因子：
1.7
通讯作者：
SADE, J
中科院分区：
文献类型：
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作者：
BERNHEIM, J;SADE, J
恶性外耳道炎（M.E.O.）外耳道皮肤损害的报告是非常少的。为了评估这个问题，我们研究了45个皮肤活检的皮肤病变，从40个M.E.O. 23例来自覆盖耳结构的骨性部分的区域，7例来自外耳道的软骨部分，15例来自两个部分。9例表皮正常，16例表皮增厚，20例表皮棘层增厚和假上皮瘤样增生。真皮中胶原蛋白的量是正常的，但它被炎症过程浸润。在16例活检中观察到急性炎症，23例为亚急性炎症，6例为慢性炎症。急性和慢性变化的混合存在于18个活检。未检测到血管系统的重大异常。M.E.O.的病理特征涉及外耳道骨性部分中炎症的典型地形分布。
Reports concerning the lesions of the skin coverage of the external ear canal in malignant external otitis (M.E.O.) are very few. To evaluate this problem, we studied the skin lesions of 45 skin biopsies from 40 M.E.O. patients, 23 from regions covering the osseous part of the ear structure, seven from the cartilaginous part of the external canal and 15 from both parts. The epidermis was normal in nine, thickened in 16, with acanthotic thickening and pseudoepitheliomatous hyperplasia in 20. In the dermis the amount of collagen was normal, but it was infiltrated by the inflammatory process. Acute inflammation was observed in 16 biopsies, subacute in 23, chronic in six. A mixture of acute and chronic changes was present in 18 biopsies. No major abnormalities of the vasculature could be detected. The distinguishing pathological feature of M.E.O. concerns the typical topographic distribution of the inflammation in the osseous part of the external ear canal.