Separating individual skin conductance responses in a short interstimulus-interval paradigm

Separating individual skin conductance responses in a short interstimulus-interval paradigm
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DOI:
10.1016/j.jneumeth.2005.02.001
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发表时间:
2005-07-15
影响因子:
3
通讯作者:
Gordon, E
Gordon, E
中科院分区:
医学4区
文献类型:
--
作者:
Alexander, DM;Trengove, C;Gordon, E

文献摘要

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我们描述了一种测量皮肤电导响应的新方法,旨在克服皮肤电导响应重叠的问题。该方法基于以下假设:潜在的sudomotor神经信号具有比皮肤电导信号本身更短的时间常数,并且sudomotor脉冲作为离散的、分离的事件到达。通过将皮肤电导信号转换为具有更短时间常数的时间序列,我们能够提取估计的底层驱动信号中的分离峰。然后使用分离的驱动器峰值来重新估计每个个体的皮肤电导响应。该方法是自动化的,并应用于735名受试者的规范数据库,在听觉怪异范式期间测量皮肤电导。(c) 2005 Elsevier B.V.版权所有
We describe a new method for measuring skin conductance responses, designed to overcome the problem of overlapping skin conductance responses. The method relies on the assumptions that the underlying sudomotor nerve signal has a shorter time-constant than the skin conductance signal itself, and that the sudomotor bursts arrive as discrete, separated events. By converting the skin conductance signal into a time-series with a shorter time-constant, we are able to extract the separated peaks in the estimated underlying driver signal. The separated driver peaks are then used to re-estimate each individual skin conductance response. The method is automated and applied to a normative database of 735 subjects, for which skin conductance was measured during an auditory oddball paradigm. (c) 2005 Elsevier B.V. All rights reserved.