PERINATAL OUTCOME IN PREGNANCIES COMPLICATED BY PULMONARY TUBERCULOSIS
PERINATAL OUTCOME IN PREGNANCIES COMPLICATED BY PULMONARY TUBERCULOSIS
复制标题
DOI：
10.1016/0020-7292(94)90064-7
复制
发表时间：
1994-02-01
影响因子：
3.8
通讯作者：
GHOSH, K
中科院分区：
文献类型：
--
作者：
JANA, N;VASISHTA, K;GHOSH, K
目的：评价妊娠合并活动性肺结核的围产儿结局。方法。对79例肺结核孕妇与316例年龄、胎次、社会经济地位相近的正常孕妇的围产儿结局进行了比较。结果：结核母亲所生婴儿的平均出生体重（2649 g）比对照组低215 g （P < 0.001）。肺结核与早产（22.8%比11.1% P < 0.01）、胎龄小（20.2%比7.9%,P < 0.005）和低出生体重新生儿（34.2%比16.5%,P < 0.001）增加约2倍相关，与围产期死亡增加6倍相关（10.1%比1.6%,P < 0.001）。在诊断较晚、治疗不完全和不规范以及肺部病变晚期的病例中，不良的围产期结局是明显的。结论：孕产妇结核病是一种高危围产期疾病。该研究强调需要对结核病进行早期诊断和治疗，最好是在怀孕前，对患有结核病的母亲进行定期医疗监督和持续的围产期护理。
OBJECTIVES: To assess the perinatal outcome of pregnancies complicated by active pulmonary tuberculosis. METHODS. The perinatal outcome of 79 gravidas with pulmonary tuberculosis was compared with that of 316 normal gravidas of similar age, parity and socioeconomic status. RESULTS: The mean birthweight of infants (2649 g) born to tuberculous mothers was 215 g less than that of control group (P < 0.001). Pulmonary tuberculosis was associated with an approximate 2-fold increase in prematurity (22.8% vs. 11.1% P < 0.01), small for gestational age (20.2% vs. 7.9%, P < 0.005) and low birthweight neonates (34.2% vs. 16.5%, P < 0.001), and 6-fold increase in perinatal deaths (10.1% vs. 1.6%, P < 0.001). The adverse perinatal outcome was pronounced in cases with late diagnosis, incomplete and irregular treatment, and advanced pulmonary lesions. CONCLUSIONS: Maternal tuberculosis is a high-risk perinatal condition. The study emphasizes the need for early diagnosis and treatment of tuberculosis, preferably before pregnancy, regular medical supervision and goon perinatal care for tuberculous mothers.