A novel method to improve sow reproductive performance: Combination of pre-weaning immunization against inhibin and post-insemination hCG treatment

A novel method to improve sow reproductive performance: Combination of pre-weaning immunization against inhibin and post-insemination hCG treatment
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提高母猪繁殖性能的新方法:断奶前抑制素免疫与授精后 hCG 治疗相结合

DOI:
10.1016/s2095-3119(20)63225-7
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发表时间:
2020-09-01
影响因子:
4.8
通讯作者:
Shi Zhen-dan
Shi Zhen-dan
中科院分区:
农林科学1区
文献类型:
--
作者:
Guo Ri-hong;He Pei-yuan;Shi Zhen-dan

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通过体内和体外实验验证了抑制素免疫与hCG联合治疗提高母猪繁殖性能的可行性。在体内试验中,106头母猪在断奶前7天注射抑制素免疫原,56头未注射抑制素免疫原的母猪作为对照。对断奶后第5天出现发情行为的母猪进行人工授精。在授精后第5天,50头经抑制素免疫的母猪接受1 000 IU人绒毛膜促性腺激素(hCG)注射。结果表明,断奶前免疫抑制素可轻微提高仔猪总窝产仔数(P=0.068),显著提高仔猪活窝产仔数(P=0.044)。三组产仔率和活窝数总体差异有显著性(P=0.10),总窝数差异不显著(P=0.18)。在体外实验中,激活素和hCG剂量依赖性抑制(P
The feasibility of a novel method to improve sow reproductive performance by combining inhibin immunization and hCG treatment was tested using in vivo and in vitro experiments. In the in vivo experiment, 106 sows were administered an inhibin immunogen on day 7 prior to weaning, and 56 non-treated sows served as the controls. Sows exhibiting oestrous behaviour on day 5 after weaning were artificially inseminated. On day 5 post-insemination, a subset of 50 inhibin-immunized sows received an injection of 1 000 IU human chorionic gonadotropin (hCG). Our results showed that pre-weaning immunization against inhibin marginally improved (P=0.068) total litter size and significantly increased (P=0.044) the live litter size. The overall differences in farrowing rates and live litter size tended toward significance (P=0.10) in the three groups, and the differences in total litter size were not significant (P=0.18). In the in vitro experiment, activin and hCG dose-dependently suppressed (P