Glycosaminoglycans in human cerebral tumors. Part II. Histochemical findings and correlations.
Glycosaminoglycans in human cerebral tumors. Part II. Histochemical findings and correlations.
复制标题
人脑肿瘤中的糖胺聚糖。
作者：
M. Giordana;A. Bertolotto;A. Mauro;A. Migheli;S. Pezzotta;G. Racagni;D. Schiffer
本文用阿新蓝染色法对224例人脑肿瘤中糖胺聚糖的发生和分布进行了组织化学研究。在正常的瘤周灰质中，嗜钙性比白色物质中强，并证明了HA和CS的存在。在胶质瘤组中，由于HA和CS，嗜酸细胞主要与浸润皮质的存在有关。在其他肿瘤中，组织化学显示GAG与胶原、网硬蛋白、中胚层区等有关。每个肿瘤的血管显示HA、CS和HS阳性染色。尽管糖胺聚糖在脑肿瘤中的意义尚不清楚，但组织化学结果与第一部分中报道的生物化学结果一致。
The occurrence and the distribution of GAGs have been studied histochemically in 224 human cerebral tumors by means of Alcian blue techniques. In the normal peritumoral gray matter the alcianophilia is stronger than in the white matter and demonstrated the presence of HA and CS. In the glioma group the alcianophilia, due to HA and CS, is mainly related to the presence of infiltrated cortex. In the other tumors, GAGs are histochemically disclosed in relation to collagen, reticulin, mesodermic areas, etc. The vessels of every tumor show a positive staining for HA, CS and HS. The histochemical findings are consistent with the biochemical ones as reported in Part I, even though the significance of GAGs in cerebral tumors remains unknown.