Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts
Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts
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DOI：
10.1097/ico.0b013e318169d698
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发表时间：
2008-06-01
期刊：
影响因子：
2.8
通讯作者：
Seiler, Theo
中科院分区：
文献类型：
--
作者：
Iseli, Hans Peter;Thiel, Michael A.;Seiler, Theo
目的：评价紫外线-角膜交联（CXL）治疗感染性角膜炎的疗效。方法：5例感染性角膜炎合并角膜熔化患者在苏黎世大学屈光与眼科医院门诊部接受CYCL治疗。当感染对全身和局部抗生素治疗无反应时，进行CXL。交联后随访1 ~ 9个月。结果：在所有病例中，CXL治疗后角膜融化的进展停止。紧急角膜移植术是没有必要的5 cases.Conclusions：CXL是治疗难治性感染性角膜炎，以避免紧急角膜移植术患者一个很有前途的选择。
Purpose: To evaluate the efficacy of ultraviolet-corneal cross-linking (CXL) for treating infectious melting keratitis.Methods: Five patients with infectious keratitis associated with corneal melting were treated with CYCL at the outpatient departments of the Institut fur Refraktive und Ophthalmo-Chirurgie and the eye hospital at the University of Zurich. CXL was performed when the infection did not respond to systemic and topical antibiotic therapy. Follow-up after cross-linking ranged from 1 to 9 months.Results: In all cases, the progression of corneal melting was halted after CXL treatment. Emergency keratoplasty was not necessary in any of the 5 cases presented.Conclusions: CXL is a promising option for treating patients with therapy-refractory infectious keratitis to avoid emergency keratoplasty.