Biomechanical and histologic observations of vocal fold fibrous proteins

Biomechanical and histologic observations of vocal fold fibrous proteins
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DOI:
10.1177/000348940010900115
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发表时间:
2000-01-01
影响因子:
1.4
通讯作者:
Hammond, TH
Hammond, TH
中科院分区:
医学3区
文献类型:
--
作者:
Gray, SD;Titze, IR;Hammond, TH

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本文讨论了声带的分子组成和纤维分子与组织的生物力学和生理性能的关系。细胞外基质的组分可分为纤维蛋白和间质蛋白。纤维蛋白质,包括胶原蛋白和弹性蛋白,是本报告的重点。弹性蛋白浓度随声带组织深度而变化。弹性蛋白随年龄变化的报道,但存在一些争议。应力和应变的生物力学术语(以及人类声带的应力-应变曲线)与声带的纤维蛋白有关。纤维蛋白质,它们在压力中的作用,以及它们对音高动态范围的影响。
This article discusses the molecular composition of the vocal fold and the relationship of fibrous molecules to the biomechanical and physiological performance of the tissue. The components of the extracellular matrix may be divided into fibrous proteins and interstitial proteins. The fibrous proteins, consisting of collagens and elastins, are the focus of this report. Elastin concentration varies by tissue depth in the vocal folds. Variation of elastin by age is reported, bur some controversy exists. The biomechanical terms of stress and strain (and stress-strain curves of human vocal folds) are related to the fibrous proteins of the vocal folds. The fibrous proteins, their role in stress, and their effect on the dynamic range of vocal pitch are presented.