Urinary albumin in space missions.

Urinary albumin in space missions.
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DOI:
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发表时间:
2002-07
期刊:
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology
影响因子:
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通讯作者:
M. Cirillo;N. D. De Santo;M. Heer;P. Norsk;B. Elmann-Larsen;L. Bellini;D. Stellato;C. Drummer
M. Cirillo;N. D. De Santo;M. Heer;P. Norsk;B. Elmann-Larsen;L. Bellini;D. Stellato;C. Drummer
中科院分区:
其他
文献类型:
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作者:
M. Cirillo;N. D. De Santo;M. Heer;P. Norsk;B. Elmann-Larsen;L. Bellini;D. Stellato;C. Drummer

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蛋白尿是太空任务的假设,但研究数据缺失。研究人员分析了宇航员在和平号空间站和地面(对照组)执行太空任务期间收集的冷冻尿液样本中的尿白蛋白,作为蛋白尿的指标。尿白蛋白用双抗体放射免疫法测定。24小时尿白蛋白在太空比在地面平均低27.4%;差异有统计学意义。低尿白蛋白排泄可能是暴露于失重(微重力)的另一个影响。
Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity).