Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog.

Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog.
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DOI:
10.1002/anie.200802901
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发表时间:
2008
影响因子:
16.6
通讯作者:
Naismith, James H.
Naismith, James H.
中科院分区:
化学1区
文献类型:
--
作者:
Oke, Muse;Ching, Rosalind Tan Yan;Carter, Lester G.;Johnson, Kenneth A.;Liu, Huanting;McMahon, Stephen A.;White, Malcolm F.;Bloch, Carlos, Jr.;Botting, Catherine H.;Walsh, Martin A.;Latiff, Aishah A.;Kennedy, Malcolm W.;Cooper, Alan;Naismith, James H.

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Ranasmurfin是一种不寻常的蓝色蛋白质,从马来西亚树蛙Polypedates leucomystax的巢穴中分离出来,显示出生物分子泡沫所显示的丰富的化学多样性。许多种类的热带青蛙使用泡沫来保护脆弱的卵和发育中的胚胎免受环境挑战。这些巢穴作为微型生态系统,包含一系列新的蛋白质和其他大分子,其功能与泡沫稳定和粘附、抗微生物降解、捕食或脱水有关,为胚胎发育提供了一个生物相容的环境。
Ranasmurfin is an unusual blue protein isolated from the nests of a Malaysian tree frog, Polypedates leucomystax, showing the rich chemical diversity displayed by biomolecular foams. Many species of tropical frogs use foams to protect delicate eggs and developing embryos against environmental challenges. These nests act as miniature ecosystems containing a spectrum of novel proteins and other macromolecules with functions related to foam stabilization and adhesion, resistance to microbial degradation, predation, or dehydration, providing a biocompatible environment for embryonic development.Thisworkformspartofourwiderstudyofthe intriguing physical and chemical properties of biofoams as unusual examples of biological soft matter.
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