Structural changes of poly-L-lysine in solution and lyophilized form

Structural changes of poly-L-lysine in solution and lyophilized form
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DOI:
10.1039/b807385f
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发表时间:
2008-01-01
影响因子:
3.3
通讯作者:
Tominaga, Keisuke
Tominaga, Keisuke
中科院分区:
化学2区
文献类型:
--
作者:
Kambara, Ohki;Tamura, Atsuo;Tominaga, Keisuke

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已经通过各种光谱技术研究了聚-L-赖氨酸的两种结构变化;一种是在冻干过程中快速冷冻期间溶液中的无规卷曲样品到α-螺旋和β-折叠的混合物的结构变化,另一种是冻干样品从α-螺旋到β-折叠结构的压力诱导的结构变化。
Two structural changes of poly-L-lysine have been studied by various spectroscopic techniques; one is a structural change of a random coil sample in solution to a mixture of alpha-helix and beta-sheet during rapid freezing in the lyophilizing process, and the other is a pressure-induced structural change from an alpha-helix to a beta-sheet structure for a lyophilized sample.