Effect of treatment with intravenous immunoglobulin on quality of life in patients with stiff-person syndrome
Effect of treatment with intravenous immunoglobulin on quality of life in patients with stiff-person syndrome
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DOI：
10.1002/mds.10043
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发表时间：
2002-05-01
影响因子：
8.6
通讯作者：
Brown, P
中科院分区：
文献类型：
--
作者：
Gerschlager, W;Brown, P
静脉注射免疫球蛋白（IVIG）对僵人综合征（SPS）的治疗效果仅在病例报告或开放标签研究的临床结果中进行了描述。我们调查 IVIG 是否可以改善 SPS 的生活质量 (QoL)。六名患有经典 SPS 的患者完成了通用 QoL 工具。在治疗前以及完成 IVIG 疗程后 2 周进行 SF-36 和视觉模拟评分 (VAS)。 SF-36 疼痛、社交功能、一般心理健康方面的分项评分有显着改善。和能量活力与治疗。 VAS 也显着改善。我们得出的结论是，IVIG 治疗可改善 SIPS 的生活质量。 (C) 2002 年运动障碍协会。
The therapeutic effects of intravenous immunoglobulin (IVIG) on the stiff-person syndrome (SPS) have been described exclusively in case reports or open-label studies in terms of clinical outcomes. We investigate whether IVIG improves quality of life (QoL) in the SPS. Six patients with the classic form of SPS completed a generic QoL instrument. the SF-36, and a Visual Analogue Scale (VAS) before treatment as well as 2 weeks after completion of a course of IVIG. There was significant improvement in the SF-36 subscores for pain, social functioning, general mental health. and energy-vitality with treatment. The VAS also improved significantly. We conclude that treatment with IVIG improves QoL in the SIPS. (C) 2002 Movement Disorder Society.