Behavioral activities collected through smartphones and the association with illness activity in bipolar disorder
Behavioral activities collected through smartphones and the association with illness activity in bipolar disorder
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DOI：
10.1002/mpr.1502
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发表时间：
2016-12-01
影响因子：
3.1
通讯作者：
Kessing, Lars Vedel
中科院分区：
文献类型：
--
作者：
Faurholt-Jepsen, Maria;Vinberg, Maj;Kessing, Lars Vedel
智能手机在双相情感障碍（BD）的监护中很有用。反映疾病活动的客观智能手机数据可以促进早期治疗，并作为疗效试验的结果。共有29名患有中度至重度抑郁和躁狂症状的BD患者在12周内使用基于智能手机的自我监测系统。收集关于行为活动的客观智能手机数据。每两周使用汉密尔顿抑郁评定量表和杨氏躁狂评定量表对症状进行临床评估。客观智能手机数据与症状严重程度相关。抑郁症状越严重（1）智能手机屏幕打开的时间越长/天，（2）接收的来电越多/天，（3）拨出的电话越少/天，（4）接听的来电越少/天，（5）患者在手机信号塔ID之间移动的次数越少/天。相反，躁狂症状越严重，（1）每天发送的短信越多，（2）每天的电话越长，（3）每天收到的短信中的字符数越少，（4）每天呼出电话的持续时间越短，（5）患者每天在手机信号塔ID之间移动的次数越多。此外，客观的智能手机数据能够区分情感状态。客观的智能手机数据反映疾病的严重程度，区分情感状态的BD，并可能促进患者和临床医生之间的合作。版权所有（c）2016约翰威利父子有限公司
Smartphones are useful in symptom-monitoring in bipolar disorder (BD). Objective smartphone data reflecting illness activity could facilitate early treatment and act as outcome in efficacy trials. A total of 29 patients with BD presenting with moderate to severe levels of depressive and manic symptoms used a smartphone-based self-monitoring system during 12weeks. Objective smartphone data on behavioral activities were collected. Symptoms were clinically assessed every second week using the Hamilton Depression Rating Scale and the Young Mania Rating Scale. Objective smartphone data correlated with symptom severity. The more severe the depressive symptoms (1) the longer the smartphone's screen was on/day, (2) more received incoming calls/day, (3) fewer outgoing calls/day were made, (4) less answered incoming calls/day, (5) the patients moved less between cell towers IDs/day. Conversely, the more severe the manic symptoms (1) more outgoing text messages/day sent, (2) the phone calls/day were longer, (3) the fewer number of characters in incoming text messages/day, (4) the lower duration of outgoing calls/day, (5) the patients moved more between cell towers IDs/day. Further, objective smartphone data were able to discriminate between affective states. Objective smartphone data reflect illness severity, discriminates between affective states in BD and may facilitate the cooperation between patient and clinician. Copyright (c) 2016 John Wiley & Sons, Ltd.