The complement system in rheumatoid synovitis. I. An analysis of complement component activities in rheumatoid synovial fluids.

The complement system in rheumatoid synovitis. I. An analysis of complement component activities in rheumatoid synovial fluids.
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类风湿性滑膜炎中的补体系统。

DOI:
10.1002/art.1780130601
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发表时间:
1970
影响因子:
--
通讯作者:
K. Austen
K. Austen
中科院分区:
--
文献类型:
--
作者:
S. Ruddy;K. Austen

文献摘要

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用化学计量学溶血试验测定了血清阳性或阴性类风湿关节炎或退行性关节疾病患者滑液中补体序列前四个反应成分的活性。类风湿性关节炎血清阳性组分减少的模式与通过关节内免疫过程激活补体系统的模式一致。
Stoichiometric hemolytic assays were used to measure the activities of the first four reacting components of the complement sequence in synovial fluids from patients with seropositive or seronegative rheumatoid arthritis or degenerative joint disease. The pattern of component reductions in the seropositive rheumatoid arthritis fluids was consistent with activation of the complement system by an intra-articular immunologic process.