Chitosan/poly (vinyl alcohol) films containing ZnO nanoparticles and plasticizers
Chitosan/poly (vinyl alcohol) films containing ZnO nanoparticles and plasticizers
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DOI：
10.1016/j.msec.2009.01.026
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发表时间：
2010-05-10
影响因子：
7.9
通讯作者：
Laranjeira, Mauro C. M.
中科院分区：
文献类型：
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作者：
Vicentini, Denice S.;Smania, Arthur, Jr.;Laranjeira, Mauro C. M.
本研究采用Pechini法制备了氧化锌纳米粒子，以聚酯为原料，通过柠檬酸与溶解金属离子的乙二醇反应制备氧化锌纳米粒子，并将其掺入壳聚糖（CS）和聚乙烯醇（PVA）与不同浓度的聚氧乙烯山梨醇单油酸酯T80 （T80）共混膜中。采用红外光谱（FTIR）、x射线衍射（XRD）、热重分析（TGA）、扫描电镜（SEM）、膨胀度、薄膜在Hank’s溶液中的降解情况和力学性能对膜进行了表征。此外，还对薄膜的抗菌活性进行了测试，结果表明ZnO纳米颗粒薄膜对金黄色葡萄球菌具有抗菌活性。所制备的复合膜具有抗菌活性，可作为亲水性创面和烧伤敷料使用。(C) 2009 Elsevier B.V.版权所有
In this study ZnO nanoparticles were prepared by the Pechini method from a polyester by reacting citric acid with ethylene glycol in which the metal ions are dissolved, and incorporated into blend films of chitosan (CS) and poly (vinyl alcohol) (PVA) with different concentrations of polyoxyethylene sorbitan monooleate, Tween 80 (T80). These films were characterized by infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), swelling degree, degradation of films in Hank's solution and the mechanical properties. Besides these characterizations, the antibacterial activity of the films was tested, and the films containing ZnO nanoparticles showed antibacterial activity toward the bacterial species Staphylococcus aureus. The observed antibacterial activity in the composite films prepared in this work suggests that they may be used as hydrophilic wound and burn dressings. (C) 2009 Elsevier B.V. All rights reserved.