The active metabolite of lefluonomide, A771726,inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.

The active metabolite of lefluonomide, A771726,inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.
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来氟诺米特的活性代谢物 A771726 通过直接作用于破骨细胞谱系的细胞来抑制破骨细胞的生成和骨吸收活性。

DOI:
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发表时间:
2004
期刊:
J.Bone Miner.Metab. 22
影响因子:
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通讯作者:
Y.
Y.
中科院分区:
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文献类型:
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作者:
Kobayashi;Y.;Ueyama;S.;Arai;Y.;Yoshida;Y.;Kaneda;T.;Sato;T.;Shin;K.;Kumegawa;M.;Hakeda;Y.

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