Association between electronic cigarette use and changes in quit attempts, success of quit attempts, use of smoking cessation pharmacotherapy, and use of stop smoking services in England: time series analysis of population trends

Association between electronic cigarette use and changes in quit attempts, success of quit attempts, use of smoking cessation pharmacotherapy, and use of stop smoking services in England: time series analysis of population trends
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DOI:
10.1136/bmj.i4645
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发表时间:
2016-09-13
影响因子:
105.7
通讯作者:
Brown, Jamie
Brown, Jamie
中科院分区:
医学1区
文献类型:
--
作者:
Beard, Emma;West, Robert;Brown, Jamie

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目的:评估英国电子烟普及率的变化在多大程度上与戒烟成功率、戒烟尝试以及戒烟尝试中使用特许药物和行为支持的变化有关。设计对人口趋势的系列分析。参与者来自吸烟工具包研究,该研究涉及对英格兰16岁及以上个人的重复、横断面家庭调查。2006年至2015年期间,汇总了约1200名吸烟者的季度数据。监测数据也来自国家行为支持计划;在研究期间,该计划设定了8,029,012个戒烟日期。SETTING England。主要结果衡量目前吸烟者和戒烟尝试期间使用电子烟的比率被用来预测戒烟成功。目前吸烟者使用电子烟的流行率被用来预测戒烟尝试的比率。使用电子烟的戒烟尝试百分比也被用来预测戒烟尝试,包括使用处方治疗、处方上和柜台购买的尼古丁替代疗法(NRT)以及使用行为支持。结果戒烟成功率提高了0.098%(95%可信区间0.064~0.132;P
OBJECTIVESTo estimate how far changes in the prevalence of electronic cigarette (e-cigarette) use in England have been associated with changes in quit success, quit attempts, and use of licensed medication and behavioural support in quit attempts.DESIGNTime series analysis of population trends.PARTICIPANTSParticipants came from the Smoking Toolkit Study, which involves repeated, cross sectional household surveys of individuals aged 16 years and older in England. Data were aggregated on about 1200 smokers quarterly between 2006 and 2015. Monitoring data were also used from the national behavioural support programme; during the study, 8 029 012 quit dates were set with this programme.SETTINGEngland.MAIN OUTCOME MEASURESPrevalence of e-cigarette use in current smokers and during a quit attempt were used to predict quit success. Prevalence of e-cigarette use in current smokers was used to predict rate of quit attempts. Percentage of quit attempts involving e-cigarette use was also used to predict quit attempts involving use of prescription treatments, nicotine replacement therapy (NRT) on prescription and bought over the counter, and use of behavioural support. Analyses involved adjustment for a range of potential confounders.RESULTSThe success rate of quit attempts increased by 0.098% (95% confidence interval 0.064 to 0.132; P