Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events - A randomized clinical trial
Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events - A randomized clinical trial
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DOI：
10.1001/jama.277.14.1127
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发表时间：
1997-04-09
影响因子：
120.7
通讯作者：
Beattie, C
中科院分区：
文献类型：
--
作者：
Frank, SM;Fleisher, LA;Beattie, C
目的：评估围术期体温与心脏发病率的关系。设计：比较常规体温护理(低温组)和额外补充温热护理(常温组)的随机对照试验。在学术医学中心设置手术室和外科重症监护病房。受试者-300名接受腹部、胸部或血管外科手术的患者，他们有记录有冠状动脉疾病或冠状动脉疾病的高风险。结果测量。根据热疗发生病态心脏事件(不稳定心绞痛/缺血、心脏骤停或心肌梗死)的相对风险。结果：低温组术后平均核心温度(35.4+/-0.1℃)低于常温组(36.7+/-0.1℃)(P
Objective.-To assess the relationship between body temperature and cardiac morbidity during the perioperative period.Design.-Randomized controlled trial comparing routine thermal care (hypothermic group) to additional supplemental warming care (normothermic group).Setting.-Operating rooms and surgical intensive care unit at an academic medical center.Subjects.-Three hundred patients undergoing abdominal, thoracic, or vascular surgical procedures who either had documented coronary artery disease or were at high risk for coronary disease.Outcome Measure. The relative risk of a morbid cardiac event (unstable angina/ischemia, cardiac arrest, or myocardial infarction) according to thermal treatment. Cardiac outcomes were assessed in a double-blind fashion.Results.-Mean core temperature after surgery was lower in the hypothermic group (35.4+/-0.1 degrees C) than in the normothermic group (36.7+/-0.1 degrees C) (P