Respiratory function in power plant workers exposed to nitrogen dioxide
Respiratory function in power plant workers exposed to nitrogen dioxide
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DOI：
10.1093/occmed/kqu129
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发表时间：
2014-12-01
影响因子：
5.1
通讯作者：
Triassi, M.
中科院分区：
文献类型：
--
作者：
Carbone, U.;Montuori, P.;Triassi, M.
背景电厂工人可能暴露于二氧化氮（NO2），因此可能比普通人群有更高的肺部疾病风险。目的评估电厂工人NO2暴露与肺功能异常的关系。方法1秒用力呼气量（FEV 1），用力肺活量（FVC）和用力呼气率（FER = FEV 1/FVC）与人口学特征相关，在工作中暴露于环境NO2的发电厂工人和对照组的行政雇员中的吸烟史和环境NO2暴露。结果24 h环境NO2浓度范围为1.21 ~ 7.82 mg m（-3），平均值为3.91 ± 1.51 mg m（-3）;结果表明：347名电厂工人FEV_1和FVC显著低于349名对照组（P < 0.001）。FER与年龄、环境NO2浓度、吸烟和身高显著相关。结论电厂NO2排放的职业暴露与肺功能异常显著相关。暴露于NO2排放的发电厂工人的肺活量测量可能是检测该组工人呼吸系统健康受损的早期迹象的有效手段。
Background Power plant workers are potentially exposed to nitrogen dioxide (NO2) and may therefore be at higher risk of pulmonary diseases than the general population.Aims To assess the association of NO2 exposure with spirometric abnormalities in power plant workers.Methods Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and forced expiratory ratio (FER = FEV1/FVC) were correlated with demographic characteristics, smoking history and environmental exposure to NO2 in power plant workers exposed to environmental NO2 at work and in a control group of administrative employees. Twenty-four hour environmental NO2 concentrations were measured at each workplace.Results The concentrations of environmental NO2 ranged from 1.21 to 7.82 mg m(-3) with a mean value of 3.91 + 1.51 mg m(-3). The results showed that FEV1 and FVC were significantly lower in 347 power plant workers than in the 349 controls (P < 0.001). The FER was significantly correlated with age, environmental NO2 concentration, smoking and height.Conclusions Occupational exposure to NO2 emissions in power plants is significantly associated with lung function abnormalities as assessed by spirometry. Spirometric measurements in power plant workers exposed to NO2 emissions may be an effective means of detecting early signs of impaired respiratory health in this group of workers.