Effectiveness and implementation of mPATH™-CRC: a mobile health system for colorectal cancer screening.
Effectiveness and implementation of mPATH™-CRC: a mobile health system for colorectal cancer screening.
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MPATH™-CRC的有效性和实施：用于结直肠癌筛查的移动卫生系统。
作者：
结直肠癌（CRC）筛查被广泛推荐，但未得到充分利用，尽管CRC是美国第三大诊断癌症和第二大癌症死亡原因。mPATH™程序是一个基于iPad的应用程序，旨在识别应进行CRC筛查的患者，教育他们常用的筛查测试，并帮助他们选择最佳选择，以提高CRC筛查率。mPATH™程序包括在登记时询问所有成年患者的问题（mPATH™-CheckIn），以及针对应进行CRC筛查的患者的特定模块（mPATH™-CRC）。在这项研究中，mPATH™计划通过III型混合实施有效性设计进行评估。具体而言，该研究包括三个部分：（1）一项初级保健诊所的随机分组对照试验，比较了“高接触”循证实施策略与“低接触”实施策略;（2）一项嵌套式实用研究，评估mPATH-CRC™在完成CRC筛查时的有效性;和（3）混合方法研究，评估促进或阻碍维持mPATH-CRC™等干预措施的因素。主要目的是比较在“高接触”和“低接触”实施策略之间实施后第6个月内完成mPATH™-CRC的符合CRC筛查条件的50-74岁患者的比例。通过比较实施前队列（实施前8个月）和实施后队列（实施后8个月）之间在就诊16周内完成CRC筛查的比例来评估mPATH™-CRC的有效性。这项研究将提供有关mPATH™计划实施情况及其在提高CRC筛查率方面的有效性的数据。此外，这项工作有可能产生更广泛的影响，通过确定战略，以支持持续使用其他类似的技术为基础的初级保健干预措施。ClinicalTrials.gov NCT03843957。于2019年2月18日注册。
Screening for colorectal cancer (CRC) is widely recommended but underused, even though CRC is the third most diagnosed cancer and the second leading cause of cancer death in the USA. The mPATH™ program is an iPad-based application designed to identify patients due for CRC screening, educate them on the commonly used screening tests, and help them select their best option, with the goal of increasing CRC screening rates. The mPATH™ program consists of questions asked of all adult patients at check-in (mPATH™-CheckIn), as well as a module specific for patients due for CRC screening (mPATH™-CRC). In this study, the mPATH™ program is evaluated through a Type III hybrid implementation-effectiveness design. Specifically, the study consists of three parts: (1) a cluster-randomized controlled trial of primary care clinics comparing a “high touch” evidence-based implementation strategy with a “low touch” implementation strategy; (2) a nested pragmatic study evaluating the effectiveness of mPATH-CRC™ on completion of CRC screening; and (3) a mixed-methods study evaluating factors that facilitate or impede the maintenance of interventions like mPATH-CRC™. The primary objective is to compare the proportion of patients aged 50–74 who are eligible for CRC screening who complete mPATH™-CRC in the 6th month following implementation between the “high touch” and “low touch” implementation strategies. Effectiveness of mPATH™-CRC is evaluated by comparing the proportion who complete CRC screening within 16 weeks of their visit to the clinic between a pre-implementation cohort (8 months before implementation) and a post-implementation cohort (8 months after implementation). This study will provide data on both the implementation of the mPATH™ program and its effectiveness in improving screening rates for CRC. In addition, this work has the potential to have an even broader impact by identifying strategies to support the sustained use of other similar technology-based primary care interventions. ClinicalTrials.gov NCT03843957. Registered on 18 February 2019.
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影响因子：
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作者：
Inadomi, John M.;Vijan, Sandeep;Janz, Nancy K.;Fagerlin, Angela;Thomas, Jennifer P.;Lin, Yunghui V.;Munoz, Roxana;Lau, Chim;Somsouk, Ma;El-Nachef, Najwa;Hayward, Rodney A.
通讯作者：
Hayward, Rodney A.
影响因子：
6.2
作者：
Doubeni CA;Laiyemo AO;Major JM;Schootman M;Lian M;Park Y;Graubard BI;Hollenbeck AR;Sinha R
通讯作者：
Sinha R
影响因子：
24
作者：
Chan, Wiley V.;Pearson, Thomas A.;Wells, Barbara L.
通讯作者：
Wells, Barbara L.
影响因子：
6.2
作者：
Farmer, Melissa M.;Bastani, Roshan;Ganz, Patricia A.
通讯作者：
Ganz, Patricia A.
影响因子：
5.7
作者：
Katz, Mira L.;Broder-Oldach, Ben;Paskett, Electra D.
通讯作者：
Paskett, Electra D.