Telemonitoring in heart failure patients treated by cardiac resynchronisation therapy with defibrillator (CRT-D): the TELECART Study.
Telemonitoring in heart failure patients treated by cardiac resynchronisation therapy with defibrillator (CRT-D): the TELECART Study.
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DOI：
10.1111/ijcp.12823
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发表时间：
2016-07
影响因子：
2.6
通讯作者：
Marfella R
中科院分区：
文献类型：
--
作者：
Sardu C;Santamaria M;Rizzo MR;Barbieri M;di Marino M;Paolisso G;Santulli G;Marfella R
远程监护（TM）是一种安全有效的内部心脏转复除颤器（ICD）受者监护系统。TM已被用于跟踪接受ICD和/或心脏再同步治疗除颤器（CRT-D）治疗的心力衰竭患者的临床状态信息。本研究的目的是调查TM对伴有心力衰竭的CRT-D患者的临床结果的影响。在一项多中心随机研究中，慢性心力衰竭患者，纽约心脏协会（NYHA）功能等级II或III，左束分支阻滞，严重左心室射血分数降低（LVEF < 35%）已被确定和筛选。191名患者被随机分为两组，一组接受TM的ct - d治疗，另一组接受传统门诊监测的ct - d治疗（对照组），并完成了为期12个月的研究随访。主要终点均为死因死亡、心源性死亡和因心力衰竭住院。次要终点为房颤、持续性发作、非持续性和自终止性室性心动过速、持续性室性心动过速、室性颤动、ICD冲击和CRT-D应答患者的百分比。单因素分析确定了以下预测住院的因素：TM、年龄、慢性肾脏疾病、高胆固醇血症、LVEF和NYHA类别。在多变量分析中，TM是预测心力衰竭住院的唯一因素（风险比0.6,0.42-0.79,95% CI, p = 0.002），不影响总死亡率和心脏性死亡事件。综上所述，我们的数据表明TM在预测接受CRT-D治疗的患者心力衰竭住院方面的重要性。
Telemonitoring (TM) is a safe and efficient monitoring system for internal cardioverter defibrillator device (ICD) recipients. TM has been used to track info on the clinical status of heart failure patients treated by ICD and/or cardiac resynchronisation therapy defibrillator (CRT-D). The aim of this study was to investigate the impact of TM on clinical outcomes in a population of CRT-D patients with heart failure. In a multicentre, randomised study, patients with chronic heart failure, New York Heart Association (NYHA) functional class II or III, left bundle branch block, severe left ventricle ejection fraction reduction (LVEF < 35%) have been identified and screened. One hundred and ninety-one patients have been randomised to receive either a CRT-D with TM or a CRT-D with traditional ambulatory monitoring (control group) and completed the 12-month study follow-up. Primary endpoints were all cause death, cardiac death and hospital admission for heart failure. Secondary endpoints were atrial fibrillation, sustained episodes, non-sustained and self terminated ventricular tachyarrhythmia, sustained ventricular tachycardia, and ventricular fibrillation, ICD shocks and percentage of CRT-D responder patients. Univariate analysis identified the following factors predicting hospitalisation: TM, age, chronic kidney disease, hypercholesterolaemia, LVEF and NYHA class. At multivariate analysis, TM was the only factor predicting heart failure hospitalisation (hazard ratio 0.6, 0.42–0.79, 95% CI, p = 0.002), without affecting overall mortality and cardiac deaths events. Taken together, our data indicate the importance of TM in predicting heart failure hospitalisation in patients treated with CRT-D.
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影响因子：
168.9
作者：
Hindricks, Gerhard;Taborsky, Milos;Sogaard, Peter
通讯作者：
Sogaard, Peter
影响因子：
39
作者：
Ong MK;Romano PS;Edgington S;Aronow HU;Auerbach AD;Black JT;De Marco T;Escarce JJ;Evangelista LS;Hanna B;Ganiats TG;Greenberg BH;Greenfield S;Kaplan SH;Kimchi A;Liu H;Lombardo D;Mangione CM;Sadeghi B;Sadeghi B;Sarrafzadeh M;Tong K;Fonarow GC;Better Effectiveness After Transition–Heart Failure (BEAT-HF) Research Group
通讯作者：
Better Effectiveness After Transition–Heart Failure (BEAT-HF) Research Group
DOI：
10.1056/nejmoa1010029
发表时间：
2010-12-09
期刊：
The New England journal of medicine
影响因子：
--
作者：
Chaudhry SI;Mattera JA;Curtis JP;Spertus JA;Herrin J;Lin Z;Phillips CO;Hodshon BV;Cooper LS;Krumholz HM
通讯作者：
Krumholz HM
影响因子：
158.5
作者：
Moss, Arthur J.;Hall, W. Jackson;Zareba, Wojciech
通讯作者：
Zareba, Wojciech
影响因子：
37.8
作者：
Anand, Inder S.;Carson, Peter;Bristow, Michael R.
通讯作者：
Bristow, Michael R.