Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A.
Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A.
复制标题
通过硒和维生素 A 的联合治疗方案对乳腺肿瘤发生进行化学预防。
DOI:
10.1093/carcin/2.9.915
复制
发表时间:
1981
期刊:
影响因子:
4.7
通讯作者:
Ip,MM
中科院分区:
文献类型:
--
作者:
Ip,C;Ip,MM
Mammary tumorigenesis induced in rats by 7,12-dimethylbenz[a]anthracene was markedly suppressed by combined dietary supplementation with sodium selenite and retinyl acetate; final tumor yield was reduced to 8% of control as compared with 51% and 36%, respectively, for selenium and retinyl acetate alone. A continuous intake of both agents was necessary to sustain the chemopreventive effect.