Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy

Genomic characterization and phylogenetic analysis of SARS-COV-2 in Italy
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DOI:
10.1002/jmv.25794
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发表时间:
2020-04-10
影响因子:
12.7
通讯作者:
Galli, Massimo
Galli, Massimo
中科院分区:
医学3区
文献类型:
--
作者:
Zehender, Gianguglielmo;Lai, Alessia;Galli, Massimo

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这份报告描述了从意大利伦巴第省首次爆发COVID-19的三名患者中分离的严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)的前三个完整基因组的分离、分子特征和系统发育分析。早期的分子流行病学追踪表明,SARS-CoV-2在首次报告感染病例之前的意大利几周就已存在。
This report describes the isolation, molecular characterization, and phylogenetic analysis of the first three complete genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from three patients involved in the first outbreak of COVID-19 in Lombardy, Italy. Early molecular epidemiological tracing suggests that SARS-CoV-2 was present in Italy weeks before the first reported cases of infection.