The symptoms and signs of upper airway resistance syndrome - A link to the functional somatic syndromes
The symptoms and signs of upper airway resistance syndrome - A link to the functional somatic syndromes
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DOI：
10.1378/chest.123.1.87
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发表时间：
2003-01-01
期刊：
影响因子：
9.6
通讯作者：
O'Hearn, D
中科院分区：
文献类型：
--
作者：
Gold, AR;Dipalo, F;O'Hearn, D
研究目的：功能性躯体综合征与各种病因不明的症状/体征相关。我们确定了几个这些症状/体征的患病率与睡眠呼吸障碍患者和检查的患病率之间的关系的症状/体征和严重程度的睡眠呼吸障碍。设计：一个描述性的研究，没有intervention.Setting：一所大学的睡眠障碍中心位于郊区setting.Patients或参与者：三组25连续收集的睡眠呼吸障碍患者。各组的呼吸暂停低通气指数（AHI）变化如下：上气道阻力综合征（UARS）[AHI <10/h），轻中度阻塞性睡眠呼吸暂停/低通气（OSA/H）[AHI大于或等于10至<40/h），以及中重度OSA/H（AHI大于或等于40/h）。测量和结果：患者接受全面的病史、体格检查和整夜多导睡眠图。UARS的诊断包括定量测量吸气流量和吸气努力，并证明吸气流量受限。睡眠呼吸障碍患者中女性所占比例（p = 0.001）和睡眠发作性失眠的患病率（p = 0.04），头痛（p = 0.01），肠易激综合征（p = 0.01）和α-δ睡眠（p = 0.01）与AHI组的严重程度降低相关。我们的结论是，患者UARS，轻度至中度OSA/H和中度至重度OSA/H不同，他们的症状/体征。UARS的症状/体征与功能性躯体综合征的症状/体征非常相似。
Study objectives: The functional somatic syndromes are associated with a variety of symptoms/signs of uncertain etiology. We determined the prevalence of several of those symptoms/signs in patients with sleep-disordered breathing and examined the relationship between the prevalence of the symptoms/signs and the severity of sleep-disordered breathing.Design: A descriptive study without intervention.Setting: A university sleep-disorders center located in a suburban setting.Patients or participants: Three groups of 25 consecutively collected patients with sleep-disordered breathing. Groups varied in their apnea hypopnea indexes (AHIs) as follows: Upper airway resistance syndrome (UARS) [AHI < 10/h), mild-to-moderate obstructive sleep apnea/hypopnea (OSA/H) [AHI greater than or equal to 10 to < 40/h), and moderate-to-severe OSA/H (AHI greater than or equal to 40/h).Measurements and results: Patients underwent comprehensive medical histories, physical examinations, and full-night polysomnography. The diagnosis of UARS included quantitative measurement of inspiratory airflow and inspiratory effort with demonstration of inspiratory flow limitation. The percentage of women among the patients with sleep-disordered breathing (p = 0.001) and the prevalence of sleep-onset insomnia (p = 0.04), headaches (p = 0.01), irritable bowel syndrome (p = 0.01), and alpha-delta sleep (p = 0.01) was correlated with decreasing severity of AHI group.Conclusions: We conclude that patients with UARS, mild-to-moderate OSA/H and moderate-to-severe OSA/H differ in their presenting symptoms/signs. The symptoms/signs of UARS closely resemble those of the functional somatic syndromes.