Peripheral neutron and gamma doses in radiotherapy with an 18 MV linear accelerator

Peripheral neutron and gamma doses in radiotherapy with an 18 MV linear accelerator
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DOI:
10.1093/rpd/nch135
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发表时间:
2004-01-01
影响因子:
1
通讯作者:
Struelens, L
Struelens, L
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Vanhavere, F;Huyskens, D;Struelens, L

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在放射治疗中,越来越多的人关注靶器官以外的器官所接受的剂量。随着患者生存时间的延长,发生继发性恶性肿瘤的风险需要尽可能地降低。因此,在放射治疗中,总的人体剂量是值得估计的。调强放射治疗(IMRT)的引入需要增加提供给患者的监测单元的数量。因此,使用这种技术增加外周剂量是有风险的。另一个主要被忽略的方面是当使用高于8 MeV的直线加速器时发生的中子外周剂量。我们用18 MV的瓦里安加速器对前列腺癌治疗中的伽马和中子进行了测量。测量是在自由空气中进行的,在丛状体模中的不同深度进行,并使用兰多-奥尔德森体模进行。使用这些测量来估计治疗区域外全身的有效剂量。
More and more attention is being given in radiotherapy to the doses received by organs other than the target organ. With increasing survival time of the patients, the risks of secondary malignancies need to be lowered as much as possible. So total body doses are worth estimating in radiotherapy. The introduction of intensity modulated radiotherapy (IMRT) needs an increase in the number of monitor units given to the patient. So there is a risk of increasing the peripheral doses using this technique. Another aspect, mostly neglected, is the neutron peripheral dose that occurs when LINAC energies above 8 MeV are used.We did measurements for both gammas and neutrons with an 18 MV Varian accelerator for a prostate cancer treatment. The measurements were done both free-in-air, at different depths in a plexi-phantom, and using a Rando-Alderson phantom. Effective doses for the total body outside the treatment area are estimated using these measurements.