Dynamic Regulatory Processes in the Transition From Suicidal Ideation to Action in Adults Leaving Inpatient Psychiatric Care: Protocol for an Intensive Longitudinal Study.
Dynamic Regulatory Processes in the Transition From Suicidal Ideation to Action in Adults Leaving Inpatient Psychiatric Care: Protocol for an Intensive Longitudinal Study.
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离开住院精神科护理的成年人从自杀念头到行动转变的动态监管过程：一项深入纵向研究的方案。
DOI：
10.2196/38582
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发表时间：
2022-06-30
影响因子：
1.7
通讯作者：
Brick, Leslie A.
中科院分区：
文献类型：
--
作者：
Victor, Sarah E.;Christensen, Kirsten;Johnson, Sheri L.;Van Allen, Jason;Brick, Leslie A.
关键词：
在过去的十年里，美国的自杀率稳步上升，而在精神病住院治疗出院后的几个月里，自杀风险尤其高。然而，自杀研究在检查个人内部的动态过程方面滞后，随着时间的推移，这些过程会导致已知的自杀高风险。几乎没有研究调查过日常生活中情感、认知和生理过程是如何在几分钟、几小时或几天内发生变化，从而导致自杀行为风险的。本协议描述了一项纵向研究，旨在检查现实世界中多个评估领域自杀风险的变化。具体地说，该研究包括跟踪住院精神科护理出院后已知有自杀高风险的成年人，使用自我报告、访谈、活动记录仪和行为方法来确定自杀想法和行为的近端因素。首先，我们假设，在大多数主要的自杀理论中，消极的情感体验将包含一个潜在的心理痛苦因素，这将预示着随着时间的推移，自杀想法的增加。其次，我们假设在消极情感刺激的背景下，较差的抑制控制，以及情绪相关的冲动性，将预测从自杀思想到自杀行为的转变。第三，我们假设睡眠时间短会导致自杀意念的增加，以及报告自杀想法的人自杀行为的几率增加。期望的样本量是130名过去一周有自杀想法或行为的成年人，他们正在接受住院精神病治疗。参与者将在住院期间完成一系列测量，以评估负面情感体验、情绪相关冲动、抑制控制、典型睡眠模式和相关协变量。出院后，参与者将完成为期4周的信号生态瞬时评估调查，以及抑制控制的移动行为测量，同时佩戴活动记录仪收集睡眠的客观数据。参与者将在出院后4周和8周完成关于自杀想法和行为的访谈。该研究于2020年11月由美国国立卫生研究院资助。招聘于2021年4月开始。数据收集完成后开始数据分析。本研究将阐明情感、认知和生理风险因素如何影响（或不影响）日常生活中自杀风险的个人波动，对现有的自杀理论具有重要意义。重要的是，检查的风险因素都是可以改变的；因此，研究结果将为及时、灵活、个性化、数字化干预的关键目标的确定提供信息，这些干预可用于减少情绪困扰，并预防高危人群的自杀。derr1 - 10.2196/38582
US suicide rates have risen steadily in the past decade, and suicide risk is especially high in the months after discharge from inpatient psychiatric treatment. However, suicide research has lagged in examining dynamic within-person processes that contribute to risk over time among individuals known to be at high risk of suicide. Almost no research has examined how affective, cognitive, and physiological processes change over minutes, hours, or days to confer risk of suicidal behavior in daily life. This protocol describes a longitudinal study designed to examine real-world changes in risk of suicide across multiple assessment domains. Specifically, the study involves following adults known to be at high risk of suicide after discharge from inpatient psychiatric care using self-report, interview, actigraphy, and behavioral methods to identify proximal contributors to suicidal thoughts and behaviors. First, we hypothesize that negative affective experiences, which are featured in most major suicide theories, will comprise a latent factor indicative of psychache (emotional pain), which will predict increases in suicidal thinking over time. Second, we hypothesize that poor inhibitory control in the context of negative affective stimuli, as well as emotion-related impulsivity, will predict the transition from suicidal thinking to suicidal behavior over time. Third, we hypothesize that short sleep duration will precede within-person increases in suicidal ideation as well as increased odds of suicidal behavior among those reporting suicidal thoughts. The desired sample size is 130 adults with past-week suicidal thoughts or behaviors who are receiving inpatient psychiatric treatment. Participants will complete a battery of measures while on the inpatient unit to assess negative affective experiences, emotion-related impulsivity, inhibitory control, typical sleep patterns, and relevant covariates. After discharge from inpatient care, participants will complete 4 weeks of signal-contingent ecological momentary assessment surveys, as well as mobile behavioral measures of inhibitory control, while wearing an actigraphy device that will gather objective data on sleep. Participants will complete interviews regarding suicidal thoughts and behaviors at 4 and 8 weeks after discharge. The study was funded by the National Institutes of Health in November 2020. Recruitment began in April 2021. Data analysis will begin after completion of data collection. This study will elucidate how affective, cognitive, and physiological risk factors contribute (or do not contribute) to within-person fluctuations in suicide risk in daily life, with important implications for extant theories of suicide. Of import, the examined risk factors are all modifiable; thus, the results will inform identification of key targets for just-in-time, flexible, personalized, digital interventions that can be used to decrease emotional distress and prevent suicide among those at highest risk. DERR1-10.2196/38582
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影响因子：
7
作者：
Armey MF;Brick L;Schatten HT;Nugent NR;Miller IW
通讯作者：
Miller IW
影响因子：
12.8
作者：
Bentley KH;Maimone JS;Kilbury EN;Tate MS;Wisniewski H;Levine MT;Roberg R;Torous JB;Nock MK;Kleiman EM
通讯作者：
Kleiman EM
影响因子：
11.3
作者：
Baer, Margaret M.;LaCroix, Jessica M.;Ghahramanlou-Holloway, Marjan
通讯作者：
Ghahramanlou-Holloway, Marjan
影响因子：
3.7
作者：
Allen, Kenneth J. D.;Hooley, Jill M.
通讯作者：
Hooley, Jill M.
影响因子：
3.6
作者：
Auerbach, Randy P.;Stewart, Jeremy G.;Johnson, Sheri L.
通讯作者：
Johnson, Sheri L.