Quantitative ultrasound in the management of osteoporosis.

Quantitative ultrasound in the management of osteoporosis.
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定量超声在骨质疏松症治疗中的应用。

DOI:
10.1121/1.3385203
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发表时间:
2010
影响因子:
2.4
通讯作者:
H. Didier
H. Didier
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
M. Krieg;H. Didier

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骨矿物质密度(BMD)是骨强度和骨折风险(FR)的主要决定因素之一,但它并不是唯一的决定因素,并且骨折患者和未骨折患者之间的 BMD 值存在重叠。因此,改进策略以更好地检测将从治疗 (TT) 中受益的高 FR 患者非常重要。定量骨超声 (QUS) 是便携式的,并且比 DXA 便宜。只有少数测量脚跟的 QUS 已达到足够的验证水平,可以常规使用。他们通常测量美国波的衰减(BUA)和速度(SOS)。众所周知,有效的足跟 QUS 可以预测 PM 女性和 65 岁以上男性的脆性骨折,与 BMD 无关。然后,足跟 QUS 可以与风险评估模型中的其他临床风险因素 (CRF) 结合使用。然后,当 DXA 可用时,足跟 QUS 的主要临床用途是与 CRF 结合识别低 FR 的人群,其中不需要进一步的诊断评估。另一方面...
Bone mineral density (BMD) is one of the major determinants of bone strength and fracture risk (FR), but it is not the only determinant, and overlap exists in BMD values between patients with and without fractures. It is therefore important to improve the strategy in better detecting patients at high FR who will benefit from treatments (TT). Quantitative bone US(QUS) are portable and less expensive than DXA. Only few QUS measuring the heel have reached a sufficient level of validation to be routinely used. They usually measure the attenuation (BUA) and the velocity (SOS) of the US wave. It is well established that valid heel QUSs predict fragility fracture in PM women and men >65, independent of BMD. Then, heel QUS can be used in combination with other clinical risk factors (CRFs) in a model of risk assessment. Then, when DXA is available, the primary clinical use of heel QUS is to identify, in conjunction with CRF, a population at low FR in which no further diagnostic evaluation is necessary. On the othe...
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发表时间: 2007-11-01
影响因子: 158.5
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