Acute retinal necrosis caused by reactivation of herpes simplex virus type 2.
Acute retinal necrosis caused by reactivation of herpes simplex virus type 2.
复制标题
2型单纯疱疹病毒再激活引起的急性视网膜坏死。
DOI：
10.1016/s0002-9394(14)72900-9
复制
发表时间：
1994
影响因子：
4.2
通讯作者：
Rosenbaum,JT
中科院分区：
文献类型：
--
作者：
Thompson,WS;Culbertson,WW;Smiddy,WE;Robertson,JE;Rosenbaum,JT
急性视网膜坏死是坏死性视网膜炎的一种严重形式。急性视网膜坏死已被证明是由水痘带状疱疹病毒和 1 型单纯疱疹病毒引起。我们治疗了 3 名明显由潜伏的 2 型单纯疱疹病毒复发引起的急性视网膜坏死患者。原发性病毒感染可能是先天性的，有两名患者记录有围产期单纯疱疹病毒 2 型感染。两名患者存在双侧脉络膜视网膜疤痕，两人均无眼部疱疹感染史，提示较早发生过亚临床脉络膜视网膜炎。在每种情况下，眼周外伤均先于视网膜炎发生两到三周。这些病例显然是由创伤引起的潜伏病毒重新激活引起的，而不是原发感染的发作。
Acute retinal necrosis is a severe form of necrotizing retinitis. Acute retinal necrosis has been demonstrated to be caused by varicella-zoster virus and herpes simplex virus type 1. We treated three patients with acute retinal necrosis apparently caused by recrudescence of latent herpes simplex virus type 2. Primary viral infection was probably congenital, with documented perinatal herpes simplex virus type 2 infection in two patients. Bilateral chorioretinal scars were present in two patients, neither of whom had a history of ocular herpetic infection, suggesting that earlier subclinical chorioretinitis had occurred. In each case, periocular trauma preceded the development of retinitis by two to three weeks. These cases are evidently caused by trauma-induced reactivation of latent virus rather than the onset of a primary infection.