Pattern of leukocytes in the blood of healthy African neonates.
Pattern of leukocytes in the blood of healthy African neonates.
复制标题
健康非洲新生儿血液中白细胞的模式。
作者：
A. Scott;A. Okolo;J. Omene;S. I. Ukpe
在出生后的前4周内，对107例足月、40例早产和35例足月非洲新生儿进行了一系列白细胞计数。此外，对随机选择的85例新生儿进行WBC分类计数。测定每种细胞类型的绝对量和相对量。新生儿期白细胞计数的主要特征为：平均白细胞计数为12，580个细胞/mm 3第1天（范围3，500 - 20，500），研究的三组中的任何两组之间均未观察到统计学差异;到第7天平均白细胞计数下降，在整个新生儿期保持稳定，中性粒细胞计数为5，第1天670个细胞/mm 3（范围980- 12，900）。这一数字无论是相对数字还是绝对数字都比欧洲和北美报告的婴儿数字低得多。最后，淋巴细胞计数始终高于欧洲和北美的可比报告。恒定的白细胞计数，特别是中性粒细胞计数，可能是重要的检测感染的非洲新生儿。
Serial leukocyte counts were performed on 107 full-term, 40 preterm and 35 postterm African neonates during the first 4 weeks of life. In addition, WBC differential counts were done on 85 of these neonates, selected randomly. Both the absolute and relative amounts of each cell type were determined. The main features of leukocyte counts during the neonatal period were: a mean leukocyte count of 12,580 cells/mm3 (range 3,500-20,500) on day 1, with no statistical difference observed between any two of the three groups studied; a decline in mean leukocyte count by day 7 which remained stable throughout the neonatal period, and a neutrophil count of 5,670 cells/mm3 (range 980-12,900) on day 1. This figure is much lower, both in relative and absolute numbers, than that reported for babies in Europe and North America. Lastly, the lymphocyte count was consistently higher than in comparable reports from Europe and North America. The constant leukocyte count, particularly that of neutrophils, may be of importance in detecting infected African neonates.