Distinct neural correlates for resolving stroop conflict at inhibited and noninhibited locations in inhibition of return
Distinct neural correlates for resolving stroop conflict at inhibited and noninhibited locations in inhibition of return
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DOI：
10.1162/jocn.2006.18.11.1937
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发表时间：
2006-11-01
影响因子：
3.2
通讯作者：
Zhou, Xiaolin
中科院分区：
文献类型：
--
作者：
Chen, Qi;Wei, Ping;Zhou, Xiaolin
研究表明，前扣带皮层（ACC）和背外侧前额叶皮层（DLPFC）与冲突控制密切相关。然而，当冲突控制过程与空间注意定向相互作用时，这些“执行”脑区将如何发挥作用仍不清楚。在经典的空间线索范式中[Posner，M.一、& Cohen，Y.（1984年）。视觉定向的组成部分。In H. Bouma & D. G. Bouwhuis（Eds.），注意力和性能X（pp. 531-556）。新泽西州希尔斯代尔：Erlbaum]，如果提示和目标之间的时间间隔大于300毫秒，则与未提示位置相比，当目标出现在提示位置时，对目标的反应延迟。返回抑制（IOR）的这种效应可以改变Stroop冲突的解决，使得Stroop干扰效应在线索（抑制）位置消失[Vivas，A. B.，& Fuentes，L. J. Stroop干扰在返回抑制中受到影响。Psychonomic Bulletin and Review，8，315-323，2001]。在这个事件相关的功能磁共振研究中，我们调查的差异反应前干扰，反应干扰和空间定向之间的相互作用的神经机制。两种类型的Stroop词[不一致的反应合格的词（IE），不一致的反应不合格的词（II）]和中性词被呈现在线索或非线索的位置。与线索位置相比，在非线索位置显著的反应前干扰激活了左吻侧ACC。此外，尽管在反应前和反应水平上都存在冲突的IE单词在提示位置没有造成显着的行为干扰，但与未提示位置相比，它们激活了左侧DLPFC。此外，中性词在行为上表现出显著的返回抑制效应，中性词激活了相对于线索位置的非线索位置的左额叶眼场。这些结果表明，左吻侧ACC参与反应前冲突与IOR之间的相互作用，而左DLPFC参与反应冲突与IOR之间的相互作用。此外，在空间搜索过程中，FEF参与将注意力转移到新的位置。
It is well documented that the anterior cingulate cortex (ACC) and the dorsolateral prefrontal cortex (DLPFC) are intensively involved in conflict control. However, it remains unclear how these "executive" brain regions will act when the conflict control process interacts with spatial attentional orienting. In the classical spatial cueing paradigm [Posner, M. I., & Cohen, Y. (1984). Components of visual orienting. In H. Bouma & D. G. Bouwhuis (Eds.), Attention and performance X (pp. 531-556). Hillsdale, NJ: Erlbaum], response to a target is delayed when it appears at the cued location compared with at the uncued location, if the time interval between the cue and the target is greater than 300 msec. This effect of inhibition of return (IOR) can alter the resolution of Stroop conflict such that the Stroop interference effect disappears at the cued (inhibited) location [Vivas, A. B., & Fuentes, L. J. Stroop interference is affected in inhibition of return. Psychonomic Bulletin and Review, 8, 315-323, 2001]. In this event-related functional magnetic resonance study, we investigate the differential neural mechanisms underlying interactions between pre-response interference, response interference, and spatial orienting. Two types of Stroop words [incongruent response-eligible words (IE), incongruent response-ineligible words (II)] and neutral words were presented either at the cued or uncued location. The significant pre-response interference at the uncued location activated the left rostral ACC as compared with at the cued location. Moreover, although the IE words which have conflicts at both pre-response and response levels did not cause significant behavioral interference at the cued location, they activated the left DLPFC as compared with at the uncued location. Furthermore, neutral words showed significant IOR effects behaviorally, and they activated the left frontal eye field (FEF) at the uncued location relative to the cued location. These results suggest that the left rostral ACC is involved in the interaction between pre-response conflict and IOR, whereas the left DLPFC is involved in the interaction between response conflict and IOR. Moreover, the FEF is involved in shifting attentional focus to novel locations during spatial search.